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Search Results for " estrogen "

20

Compounds

Cat No. Product Name Synonyms Targets
T15249 Estrogen receptor modulator 1 Estrogen Receptor/ERR
Estrogen receptor modulator 1 causes regression of Tamoxifen-resistant, hormone-independent xenograft tumors. Estrogen receptor modulator 1 is an orally active and selective estrogen receptor modulator (SERM) (pIC50: 0.4...
T78646 Estrogen receptor antagonist 8 Estrogen Receptor/ERR
Estrogen Receptor Antagonist 8 exhibits potent antagonistic activity against the estrogen receptor (ER), demonstrating effective anti-uterotrophic potential in vivo, with an EC50 value of 4.160 μM.
T11237 Camizestrant Estrogen receptor antagonist 2 Estrogen Receptor/ERR
Camizestrant (Estrogen receptor antagonist 2) is an antagonist of the estrogen receptor and can be used in studies about ER+ HER2-advanced breast cancer[1].
T11236 Giredestrant tartrate Estrogen receptor antagonist 1 Estrogen Receptor/ERR , Others
Giredestrant tartrate (Estrogen receptor antagonist 1) is a novel, orally active, selective and effective non-steroidal estrogen receptor antagonist. Giredestrant tartrate strongly binds to ER, resulting in the failure o...
T40893 Estrogen receptor modulator 6
Estrogen receptor modulator 6 (compound 3a) is a highly specific and potent agonist of the estrogen receptor (ER) β with a remarkable affinity (K i = 0.44 nM). This compound exhibits an impressive 19-fold selectivity for...
T19988 Conjugated Estrogen sodium Conjugated estrogens,Conest,HSDB 3076,Kestrin,Estrogens, conjugated,TAG-39
Conjugated estrogens are medicine that contains a mixture of estrogen hormones. It is used to treat moderate to severe hot flashes, changes in and around the vagina, and other symptoms of menopause or low amounts of estr...
T63277 Estrogen receptor antagonist 2
Estrogen receptor antagonist 2 is a selective down-regulator of estrogen receptor. Estrogen (E2) and estrogen alpha receptor (ERα) are important drivers of breast cancer development. estrogen receptor antagonist 2 has re...
T63914 Estrogen receptor antagonist 3
Estrogen receptor antagonist 3 is a potent degradation agent of the estrogen receptor (ER). Estrogen signalling systems play an important role in the regulation of cell growth, differentiation and apoptosis, and Estrogen...
T63106 Estrogen receptor antagonist 4
Estrogen Receptor Antagonist 4 is a potent inhibitor of the estrogen receptor (ER), crucial for regulating cell growth, differentiation, and apoptosis. This compound holds promise for cancer research[1].
T79109 Estrogen receptor modulator 8 Estrogen Receptor/ERR
Estrogen Receptor Modulator 8 (compound 4) is an orally active inhibitor targeting Estrogen Receptor/ERR α with potent efficacy (IC50 = 0.437 nM in MCF-7 cells) and effectively hampers MCF-7 cell proliferation (IC50 = 0....
T62952 Estrogen receptor antagonist 5
Estrogen receptor antagonist 5 is a potent antagonist of the Estrogen receptor. Estrogen receptor (Estrogen receptor) is a ligand-activated transcriptional regulatory protein that interacts with endogenous estrogens and ...
T63582 Estrogen receptor antagonist 1
Estrogen receptor antagonist 1 is a potent antagonist of the estrogen receptor. Estrogen receptor antagonist 1 has shown research potential in breast cancer disease.
T79064 Estrogen receptor modulator 7 Estrogen Receptor/ERR
Estrogen Receptor Modulator 7 is a potent modulator of estrogen receptors, utilized in cancer research [1].
T60293 Estrogen receptor-IN-1
Estrogen receptor-IN-1 (compound 16) is an effective estrogen receptor (ER) inhibitor with IC 50 s of 13, 5μM for ERα and Erβ, respectively [1].
T62953 Estrogen receptor antagonist 6
Estrogen receptor antagonist 6 is a potent antagonist of the Estrogen receptor. Estrogen receptor is a ligand-activated transcriptional regulatory protein that interacts with endogenous estrogens and mediates the inducti...
T61909 Estrogen receptor antagonist 7
Estrogen Receptor Antagonist 7 (Compound 13) is a potent antagonist of estrogen receptors (ER), demonstrating antiproliferative effects against breast and ovarian cancer cells, along with anticancer and anti-uterotrophic...
T82439 Estrogen receptor modulator 10 Estrogen Receptor/ERR
Compound G-5b, an estrogen receptor modulator 10, functions as an estrogen receptor (ER) antagonist (IC50=6.7 nM) and degrader (DC50=0.4 nM). It has the capability to induce apoptosis and block cells at the G1/G0 phase, ...
T62311 Estrogen receptor β antagonist 2
Estrogen receptor β antagonist 2 is a selective, potent estrogen receptor β (ERβ) antagonist that acts on Erα (IC50: 109.10 μM) and Erβ (IC50: 0.63 μM).
T62764 Estrogen receptor α antagonist 1
Estrogen receptor α antagonist 1 (compound 35) is a highly selective estrogen receptor α antagonist that acts on estrogen receptor α (IC50: 0.02 μM), estrogen receptor β (IC50. Estrogen receptor α antagonist 1 (compound ...
T4388 PHTPP Estrogen Receptor/ERR , Estrogen/progestogen Receptor
PHTPP is a selective ERβ antagonist.
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