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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP1699L | SEB Domain 144-153 acetate(210229-94-0 free base) | Others | |
This peptide is Staphylococcal Enterotoxin B domain amino acid residue 163-172. It has been shown to inhibit transcytosis of multiple staphylococcal enterotoxins, SEA, SEE, and TSST-1. | |||
TP1699 | SEB Domain (144-153) | SEB Domain 144-153 | |
This peptide is Staphylococcal Enterotoxin B domain amino acid residue 163-172. It has been shown to inhibit transcytosis of multiple staphylococcal enterotoxins, SEA, SEE, and TSST-1. | |||
T36656 | Anti-Spike-RBD Single Domain mAb | ||
The Anti-Spike-RBD Single Domain mAb is a monoclonal antibody derived from CHO cells in Alpaca. It is composed of VHH-huFc and exhibits a strong affinity for the SARS-CoV-2 RBD. [1] | |||
TP2208 | PDZ1 Domain inhibitor peptide | Others | |
Novel cyclic peptide that disrupts interaction between GluR6 and PSD-95 | |||
T40409 | Tau Peptide (275-305) (Repeat 2 domain) | ||
Tau Peptide (275-305), also known as the R2 domain fragment, represents the second repeat unit of the microtubule-binding domain of the Alzheimer's tau peptide. Tau Peptide (275-305) is considered crucial in determining ... | |||
TP2163 | SEB Domain 144-153 TFA(210229-94-0 free base) | SEB Domain (144-153) (TFA) | Others |
SEB Domain 144-153 TFA is Staphylococcal Enterotoxin B domain amino acid residue 144-153. It inhibits transcytosis of multiple staphylococcal enterotoxins, SEE, SEA, and TSST-1. | |||
T82261 | Grb2 SH2 domain inhibitor 1 | ||
Grb2 SH2 Domain Inhibitor 1 is a cyclic cell-penetrating peptide (CPP) featuring a conformationally restricted d-pro-l-pro motif ring (AF Φ Rpprrfq), where Φ represents L-naphthylalanine, R denotes D-arginine, and P indi... | |||
T75838 | PDZ1 Domain inhibitor peptide TFA | ||
PDZ1 Domain Inhibitor Peptide TFA, a cyclic peptide featuring a β-Ala lactam side chain linker, specifically targets the PDZ1 domains of postsynaptic density protein 95 (PSD-95). It effectively disrupts the GluR6/PSD-95 ... | |||
T77994 | Grb2 SH2 domain inhibitor 1 TFA | ||
Grb2 SH2 Domain Inhibitor 1 TFA is a cyclic cell-penetrating peptide (CPP) featuring a conformationally restricted d-pro-l-pro motif ring (AF Φ Rpprrfq), where Φ represents L-naphthylalanine, R signifies D-arginine, and ... | |||
T2072 | BET bromodomain inhibitor | Epigenetic Reader Domain | |
BET bromodomain inhibitor is a potent BET inhibitor. | |||
T80521 | Caveolin-1 (82-101) amide (human, mouse, rat) | Caveolin-1 scaffolding domain peptide | c-Met/HGFR |
Caveolin-1 (82-101) amide (human, mouse, rat), also known as Caveolin-1 scaffolding domain peptide, mitigates aging-related detrimental alterations in various organs and inhibits tyrosine kinases [1]. | |||
T15424 | GSK1379725A | Epigenetic Reader Domain | |
GSK1379725A is a selective BPTF ligand (Kd: 2.8 uM). It also shows no binding activity for Brd4. | |||
T11925 | M‑89 | Epigenetic Reader Domain , Histone Methyltransferase | |
M-89, a highly potent and specific inhibitor of the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction, exhibits a Kd of 1.4 nM for menin binding. This compound holds potential for treating MLL leukemia... | |||
T5440 | Dbet57 | Epigenetic Reader Domain | |
dBET57 is heterobifunctional degrader of BRD4 based on the PROTAC technology, exhibits significant degradation of BRD4BD1 with a DC50/5h of 500 nM ,and inactive on BRD4BD2 | |||
T4495 | DBET1 | Epigenetic Reader Domain | |
dBET1 is a hybrid molecule that combines (+)-JQ1 and thalidomide. It induces cereblon-dependent BET protein degradation in vitro (EC50: 430 nM) and induces apoptosis. | |||
T5130 | DBET6 | Apoptosis , Epigenetic Reader Domain | |
dBET6 is a selective and cell-permeable degrader of BET based on PROTAC (IC50: 14 nM). It has antitumor activity. | |||
T19935 | XD14 | Epigenetic Reader Domain | |
XD14 is an inhibitor of BET bromodomain (Kd of 160 nM, 170 nM, 380 nM, 490 nM, 830 nM and 850 nM for BRD4(1), BRD2(1), BRD3(1), BRD3(2), BRD2(2) and BRD4(2), respectively). | |||
T3973 | PF-CBP1 | Epigenetic Reader Domain | |
PF-CBP1 HCl is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP). It inhibits CREBBP (IC50: 125 nM) and p300 bromodomains (IC50: 363 nM). | |||
T14685 | BMS-986158 | Epigenetic Reader Domain | |
BMS-986158 is a highly effective BET inhibitor, demonstrating IC50 values of 6.6 nM in NCI-H211 small cell lung cancer (SCLC) cells and 5 nM in MDA-MB231 triple negative breast cancer (TNBC) cells. | |||
T9339 | Stafia-1 | STAT | |
Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members. |