connexin — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T82683	Connexin mimetic peptide 40GAP27
	Connexin mimetic peptide 40GAP27, corresponding to the GAP27 domain of the second extracellular loop of the dominant vascular connexin (Cx40), designated as 40Gap27, is a biologically active peptide utilized to study the...
T82684	Connexin mimetic peptide 40,37GAP26
	Connexin mimetic peptide 40,37GAP26, a biologically active peptide, matches the GAP26 domain of the extracellular loop of major vascular connexins Cx37 and Cx40, referred to as 37,40Gap26 based on Cx homology. It has bee...
TP1563	Gap19		Gap Junction Protein
	Gap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of Cx43.		Gap Junction Protein
T5192	Gap 26		Gap Junction Protein
	Gap 26 is a mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker.		Gap Junction Protein
TP1333	Gap 27		Gap Junction Protein
	Gap 27 is a peptide(Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile) derived from connexin 43 that is a selective gap junction blocker.		Gap Junction Protein
T75795	Gap 26 TFA
	Gap 26 TFA, a gap junction blocker, is a connexin mimetic peptide derived from the amino acid sequence 63-75 in the first extracellular loop of connexin 43, featuring the SHVR amino acid motif [1].
T34120L	PQ1 Succinate	PQ 1 Succinate,PQ-1 Succinate
	PQ1 Succinate, a gap junction enhancer, acts by restoring GJIC and increasing connexin expression in breast cancer cell lines while not affecting normal mammary cells.
T7732	Carbenoxolone	Biogastrone,Carbenoxolona,Carbenoxolone,Bioral	Dehydrogenase , Gap Junction Protein
	Carbenoxolone (Biogastrone) is an inhibitor of 11β-HSD and gap junction connexin channels. Carbenoxolone inhibits macrophage migration into atria and prevents the development of fatty liver disease.		Dehydrogenase , Gap Junction Protein
TP1511	Gap19 TFA (1507930-57-5 free base)	Gap19 TFA
	Gap19 TFA is a peptide derived from nine amino acids of Cx43 cytoplasmic ring (CL), an effective, selective connexin 43 (Cx43) half-channel blocker.
T78061	Peptide5 TFA		Gap Junction Protein
	Peptide5 TFA, a connexin 43 mimetic peptide, mitigates swelling, astrogliosis, and neuronal cell death in animal models of spinal cord injury. Additionally, it suppresses the NLRP3 inflammasome, functioning as an anti-in...		Gap Junction Protein
T34120	PQ1	PQ-1,PQ 1
	PQ1, as an enhancer of gap junction in SW480 human colorectal cancer cells can act by restoring GJIC and increasing connexin expression in breast cancer cell lines while not affecting normal mammary cells.
T80852	VRT-534
	VRT-534 is a compound that selectively targets connexin 26 (Cx26), demonstrating dose-responsive binding to both wild-type (WT) Cx26 and the mutant Cx26 K188N, with EC50 values of 19 μM and 5 μM, respectively. It has pot...
T61941	BMT-090605 hydrochloride
	BMT-090605 hydrochloride is an effective and selective inhibitor of connexin-2 associated kinase 1 (AAK1) (IC50=0.6 nM). BMT-090605 hydrochloride inhibits BMP-2 induced protein kinase (BIKE) (IC50=45 nM) and cyclin G-rel...
T36851	Peptide5
	Connexin43 mimetic peptide. Reduces swelling, astrogliosis, neuroinflammation and neuronal cell death following spinal cord injury ex vivo and in vivo. Exhibits analgesic effects in models of neuropathic pain. O'Carroll ...
T75820	Gap19 TFA
	Gap19 TFA is a selective and potent blocker of connexin 43 (Cx43) hemichannels, originating from nine amino acids within the Cx43 cytoplasmic loop (CL). It operates by hindering intramolecular interactions between the C-...