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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T23513 | VU10010 | VU 10010 | AChR |
VU10010 (VU 10010) is allosteric potentiator of M4 acetylcholine receptors. | |||
T23310 | SB-203186 hydrochloride | 5-HT Receptor | |
SB 203186 hydrochloride is a potent 5-HT4 receptor antagonist | |||
T16686 | Pyr10 | TRP/TRPV Channel | |
Pyr10 is a pyrazole derivative and a selective TRP cation 3 inhibitor. Pyr10 has the ability to distinguish between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1)/Orai1 channels. Pyr10 inhibits... | |||
TP2209L | Xenin 8 acetate | Xenin 8 acetate (117442-28-1 Free base) | IGF-1R |
Xenin 8 acetate is a biologically active fragment of Xenin in the neurotensin/xenopsin family. Xenin 8 acetate augments Arginine-induced insulin release (by 40%) and potentiates the glucagon responses to both Arginine (b... | |||
T67956L | Litoxetine HCl | litoxetine HCL(86811-09-8 Free base) | 5-HT Receptor |
Litoxetine HCl is a selective 5-hydroxytryptamine (5-HT) reuptake inhibitor (SSRI) and mixed 5-hydroxytryptamine antagonist used in the treatment of urinary incontinence. Litoxetine HCl in the absence of antimuscarinic c... | |||
T67959 | Pirodomast | Thrombin , Serine Protease | |
Pirodomast is a thromboxane A (TXA2) synthase inhibitor. Pirodomast inhibits leukotriene (LT) D4, C4, E4 formation and thromboxane B2 (TXB2) activity, but is weakly or ineffectively antagonistic to guinea pig bronchospas... | |||
T61309 | (R)-Oxybutynin | ||
(R)-Oxybutynin (Aroxybutynin) is an orally active muscarinic receptor antagonist, which exhibits antimuscarinic, antispasmodic, and anticholinergic activity. This compound, being the (R)-isomer of Oxybutynin, competitive... | |||
T34958 | TRK-380 | TAC301,TAC 301,TAC-301,TRK 380,TRK380 | |
TRK-380 (TAC-301) is an effective and selective β3-adrenergic receptor agonist. TRK-380 improves formalin-induced frequent urination in rats and carbachol-induced bladder contraction in dogs (a decrease of 37.6%). | |||
T61529 | Pirmenol hydrochloride | ||
Pirmenol hydrochloride functions by inhibiting I_K.ACh through the blockade of muscarinic receptors, demonstrating a potent effect with an IC_50 value of 0.1 μM for the inhibition of Carbachol-induced I_K.ACh. | |||
T37718 | Galanin (rat, mouse) (trifluoroacetate salt) | GAL (rat, mouse),Galanin (rat, mouse) (trifluoroacetate salt) | |
Galanin is a neuropeptide with diverse biological activities. [1][2][3][4][5] It binds to rat galanin (GAL) receptor subtypes GAL1-3 (IC50s = 0.339, 1.35, and 3.31 nM, respectively) and human GAL1-3 (IC50s = 0.288, 1.62,... | |||
T83697 | PAMP-12 (human, mouse, rat, porcine, bovine) TFA | Proadrenomedullin N-terminal 12 Peptide,PAMP (9-20) | |
Proadrenomedullin N-terminal 12 peptide (PAMP-12), an endogenous fragment originating from the adrenal medulla and spanning amino acids 9-20 of human PAMP-20, plays a role in causing hypotension. It functions as an agoni... |