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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15507 | Hycanthone | Etrenol(mesylate),Win 249-33 | DNA/RNA Synthesis , Topoisomerase , Parasite |
Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal. Hycanthone is a DNA intercalator that inhibits RNA synthesis and DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibit... | |||
T4569 | Lucanthone | Lucantona,Lucanthonum | DNA/RNA Synthesis , Autophagy |
Lucanthone (Lucanthonum) is an inhibitor of Apurinic endonuclease-1 (APE-1). | |||
T66154 | Paroxypropione | ||
It is an inhibitor of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) | |||
T21320 | Methoxyamine HCl | TRC102,TRC 102,Methoxyamine,TRC-102 | Others |
Methoxyamine HCl (Methoxyamine) covalently binds to apurinic/apyrimidinic (AP) DNA damage sites and inhibits base excision repair (BER), which may result in an increase in DNA strand breaks and apoptosis. Methoxyamine is... | |||
T35575 | Aldehyde Reactive Probe (trifluoroacetate salt) | ||
DNA is continually damaged by endogenous and environmental agents leading to the formation of abasic (apurinic/apyrimidinic, AP) sites that are disruptive to DNA synthesis. Aldehyde Reactive Probe (ARP) is a biotinylated... | |||
T73299 | APE1-IN-2 | Apoptosis | |
APE1-IN-2 (compound AP1), a Pt(IV) proagent, selectively targets the essential base excision repair protein apurinic/apyrimidinic endonuclease 1 (APE1). Exhibiting anticancer properties, APE1-IN-2 prompts the intracellul... |