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Search Results for " apurinic "

6

Compounds

Cat No. Product Name Synonyms Targets
T15507 Hycanthone Etrenol(mesylate),Win 249-33 DNA/RNA Synthesis , Topoisomerase , Parasite
Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal. Hycanthone is a DNA intercalator that inhibits RNA synthesis and DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibit...
T4569 Lucanthone Lucantona,Lucanthonum DNA/RNA Synthesis , Autophagy
Lucanthone (Lucanthonum) is an inhibitor of Apurinic endonuclease-1 (APE-1).
T66154 Paroxypropione
It is an inhibitor of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)
T21320 Methoxyamine HCl TRC102,TRC 102,Methoxyamine,TRC-102 Others
Methoxyamine HCl (Methoxyamine) covalently binds to apurinic/apyrimidinic (AP) DNA damage sites and inhibits base excision repair (BER), which may result in an increase in DNA strand breaks and apoptosis. Methoxyamine is...
T35575 Aldehyde Reactive Probe (trifluoroacetate salt)
DNA is continually damaged by endogenous and environmental agents leading to the formation of abasic (apurinic/apyrimidinic, AP) sites that are disruptive to DNA synthesis. Aldehyde Reactive Probe (ARP) is a biotinylated...
T73299 APE1-IN-2 Apoptosis
APE1-IN-2 (compound AP1), a Pt(IV) proagent, selectively targets the essential base excision repair protein apurinic/apyrimidinic endonuclease 1 (APE1). Exhibiting anticancer properties, APE1-IN-2 prompts the intracellul...
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