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Search Results for " antisecretory "

20

Compounds

Cat No. Product Name Synonyms Targets
TP2207 Pasireotide Acetate Somatostatin
Pasireotide Acetate is a stable cyclohexapeptide somatostatin mimic
T0081 Lafutidine FRG-8813 5-HT Receptor , Histamine Receptor
Lafutidine (FRG-8813) is a newly developed histamine H(2)-receptor antagonist, which can inhibit gastric acid secretion.
T8388 Vonoprazan TAK-438 (free base) Proton pump
Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and reflux esophagitis
T21254 Vonoprazan Fumarate TAK-438,TAK 438,Vonoprazan Fumurate,TAK438 Proton pump
Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion. Vonoprazan Fumarate (TAK438) inhibited H+,K+-ATPase activity in porcine gastric microsomes with IC50 value of 19...
T29015 Trithiozine Tresanil,Sulmetozine,Tritiozinum,Tritiozine,Tritiozina Others
Trithiozine (Tritiozinum) exhibits antisecretory and antiulcer capacity. Trithiozine can be used for research on the treatment of peptic ulcer disease and hypersecretory disorders.
T15195 Ebrotidine FI3542 Histamine Receptor
Ebrotidine (FI3542) is a competitive H2-receptor antagonist with Ki of 127.5 nM. Ebrotidine has a potent antisecretory activity and evidenced gastroprotection.
T6710 Troxipide Aplace Others
Troxipide (Aplace), a new-type systemic non-antisecretory gastric cytoprotective agent, which is mucus-secreting, anti-ulcer, and anti-inflammatory properties irrespective of pH of stomach or duodenum.
T2138 Oxyphencyclimine Hydrochloride Spazamin,Daricon,Ulcociclinina AChR
Oxyphencyclimine Hydrochloride (Ulcociclinina) is a synthetic tertiary amine and antimuscarinic agent with antispasmodic and antisecretory activities.
T0786 Clidinium bromide Ro 2-3773 AChR
Clidinium bromide (Ro 2-3773) , a synthetic anticholinergic agent, has been shown in experimental and clinical researchers to have a pronounced antisecretory and antispasmodic effect on the gastrointestinal tract. It can...
T31195 Dalcotidine KU 1257,KU-1257 Histamine Receptor
Dalcotidine (KU 1257) is a novel histamine H2 receptor antagonist with histamine H9 receptor antagonistic activity and antisecretory effects.The Ki value for binding to guinea pig cerebral cortex was 0.040 The KB value f...
T13382 Zaltidine CP-57361 Others
Zaltidine is an antagonist of H2-receptor, and has the antisecretory action.
TP2343 Lagatide
Lagatide is a synthetic heptapeptide that has antisecretory activity.
T71390 AY 29315
AY 29315 is a histamine H2-receptor antagonist with antisecretory and antiulcer activities.
T12369 Pasireotide pamoate SOM230 pamoate Others
Pasireotide pamoate is a stable cyclohexapeptide somatostatin mimic. Pasireotide pamoate exhibits antisecretory, antiproliferative, and proapoptotic activity.
T68133 Quisultazine
Quisultazine is a phenothiazine derivative with no central effects, can be classified as a non anti H2 antisecretory agent.
T36154 15(S)-15-methyl Prostaglandin E2 15(S)-15-methyl Prostaglandin E2
15(S)-15-methyl PGE2 is a potent, metabolically stable analog of PGE2. It is a potent gastric antisecretory and antiulcer compound. 15(S)-15-methyl PGE2 binds to human myometrium with twice the affinity of PGE2 and is te...
T70473 Parapenzolate Free Base
Parapenzolate Free Base is a safe and effective anticholinergic drug possessing antisecretory and antimotility properties and prolonged duration of action. Clinical investigation has shown that after an oral dose of the ...
T27092 CS-526 R-105266,R 105266,R105266
CS-526 is a proton pump inhibitor. The inhibitory mechanism of CS-526 on H+,K+-ATPase was a competitive antagonism to the K+ binding site of H+,K+-ATPase, and it was also a reversible inhibition. CS-526 has a potent anti...
T9660 Bexlosteride
Bexlosteride (LY300502), a benzoquinolinone derivative, functions as a human type I 5α-reductase inhibitor. It demonstrates metabolic inhibition, antiproliferative, and antisecretory activities specifically in LNCaP huma...
T75248 Pasireotide (diaspartate)
Pasireotide diaspartate (SOM230), a long-acting cyclohexapeptide and somatostatin analog, enhances agonist activity across somatostatin receptor subtypes (sst1/2/3/4/5, with pK i values of 8.2, 9.0, 9.1, <7.0, and 9.9, r...
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