antiestrogenic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3855	Tracheloside		Estrogen Receptor/ERR , Phosphorylase
	Tracheloside significantly decreases the activity of alkaline phosphatase (IC50: 0.31 μg/ml), a level of inhibition comparable to that of tamoxifen (IC50: 0.43 μg/ml).		Estrogen Receptor/ERR , Phosphorylase
T7999	7-Hydroxyflavanone		Anti-infection
	7-Hydroxyflavanone shows antimicrobial activity against Streptococcus pneumoniae clinical isolates.		Anti-infection
T8984	FLTX1		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	FLTX1 is a fluorescent derivative of Tamoxifen, designed to efficiently target and label intracellular Tamoxifen-binding sites (estrogen receptors) both under permeabilized and non-permeabilized conditions. Additionally,...		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T2569	Chlorotrianisene	tris(p-methoxyphenyl)chloroethylene,CTA,tri-p-anisylchloroethylene,TACE	Estrogen Receptor/ERR , Estrogen/progestogen Receptor , COX
	Chlorotrianisene (tri-p-anisylchloroethylene) is an orally bioavailable, highly lipophilic, synthetic triphenylethylene (TPE) derivative and selective estrogen receptor modulator (SERM), with predominantly estrogenic but...		Estrogen Receptor/ERR , Estrogen/progestogen Receptor , COX
T11200	Endoxifen (E-isomer)	E-Endoxifen,Endoxifen E-isomer	Estrogen Receptor/ERR
	Endoxifen E-isomer (E-Endoxifen) is the E-isomer of (Z)-Endoxifen. Endoxifen E-isomer has antiestrogenic effects.		Estrogen Receptor/ERR
TN4565	Millewanin G		Others
	Millewanin G shows antiestrogenic activity.		Others
T13415	Zuclomiphene citrate		Others
	Zuclomiphene citrate is a cis isomer of Clomiphene citrate, and has an antiestrogenic effect and can inhibit the secretion of luteinizing hormone (LH) more than the trans isomer.		Others
T26154	RU 45144	RU45144,RU-45144
	RU 45144 is an estradiol derivative with antiestrogenic activity.
T27884	LY 183648	LY-183648,LY183648
	LY 183648 has antiestrogenic activity. LY117018 inhibited PAIII metastasis to the gluteal (97%) and iliac lymph nodes (88%).
T12312	OP-1074		Estrogen/progestogen Receptor
	OP-1074 is a pure antiestrogen and a selective degrader of ER, shows specific antiestrogenic activity for ERα and ERβ.		Estrogen/progestogen Receptor
TN4566	Millewanin H		Others
	Millewanins H shows antiestrogenic activity.		Others
T61161	HIF-1α-IN-3
	HIF-1α-IN-3, also known as Compound (S)-3f, is a hypoxia-selective inhibitor of HIF-1α. It exhibits potent antiestrogenic activity [1].
T9796	22393-62-0_peak 2
	22393-62-0_peak 2 exhibits some aspects of the antiestrogenic activity and other actions that may be connected to the estrogenic properties. A mixture of the (Z)- and (E)-isomers (Broparestrol, INN) is used in dermatol...
T39259	Arzoxifene	LY353381,Arzoxifene,SERMIII
	Arzoxifene (LY353381) is an orally active selective estrogen receptor modulator (SERM) exhibiting a fixed ring structure analogous to raloxifene. This compound demonstrates potent antiestrogenic effects on breast cancer ...
T12148L	N-Desmethyltamoxifen		Others
	N-Desmethyltamoxifen, the principal metabolite of tamoxifen in humans, serves as an efficacious modulator of ceramide metabolism within human AML cells by inhibiting ceramide glycosylation, hydrolysis, and sphingosine ph...		Others
TN4731	Pachyaximine A		Antifection
	Pachyaximine A possesses significant antibacterial activity against Escherichia coli, Staphylococcus aureus, Corynebacterium diphtheriae and Corynebacterium pyrogenes. (-)-Pachyaximine A demonstrates significant activity...		Antifection
T69696	TAS-108 citrate
	TAS-108, also known as SR16234, is a synthetic, antiestrogenic steroidal compound with potential antitumor activity. TAS-108 binds to and inhibits estrogenic receptor alpha (ERa), mainly expressed in the mammary gland an...