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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14983 | Clomethiazole | Distraneurin,Chlormethiazole,5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE | P450 , GABA Receptor |
Clomethiazole (Distraneurin) is an orally active GABAA agonist and it is an anticonvulsant agent. It also has the potential for treating convulsive status epilepticus. Chlormethiazole inhibits cytochrome P450 isoforms: C... | |||
T0963 | Naltrexone hydrochloride | Depade,Trexan,Naltrexone HCl,Antaxone | Opioid Receptor |
Naltrexone hydrochloride (Naltrexone HCl) is a synthetic opioid antagonist used in the prevention of relapse of opiate addiction and alcoholism. | |||
T27939 | LY2940094 tartrate | LY2940094,LY 2940094,LY-2940094 tartrate,LY-2940094 | |
LY-2940094, a nociceptin receptor antagonist, is used potentially for the treatment of major depressive disorder and alcoholism. | |||
T73059 | Acamprosate | ||
Acamprosate, an orally active prototypic neuromodulator, is utilized in the study and treatment of alcohol dependence and alcoholism. | |||
T28888 | Surinabant | SR 147778,SR147778,SR-147778 | |
Surinabant, a cannabinoid CB1 antagonist, is used potentially for the treatment of obesity and alcoholism. | |||
T26569 | ADX71441 | ADX 71441,ADX-71441 | |
ADX71441 is a GABAB positive allosteric modulator (PAM). ADX71441 increases urinary latencies and reduces the number of urinary events and the total and average urinary volumes. ADX71441 may also mitigate alcoholism and ... | |||
T13652 | Dicarbine | Dopamine Receptor | |
Double carbene can be used for the study of schizophrenia and alcoholism. It can block dopamine receptors in various parts of the brain and prevent the reduction of conditioned defense reflexes caused by the stimulation ... | |||
T2092L | Amitifadine free base | DOV 21947,DOV-21947,DOV21,947,DOV21947,DOV 21,947,DOV-21,947 | |
Amitifadine(DOV-21947, EB-1010) is an inhibitor of the so-called triple reuptake or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) and is an antidepressant drug candidate. Amitifadine reduces binge drinking... | |||
T36947 | Pyrithiamine (hydrobromide) | ||
Pyrithiamine is the pyridine analog of thiamine that prevents growth of organisms that require intact thiamine. [1] It inhibits the growth of bacterial and fungal species at a pyrithiamine:thiamine ratio of 10:1 in growt... | |||
T79805 | 5-HT2 agonist-1 free base | 5-HT Receptor | |
Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively. It is utilized in research pertaining to depression... | |||
T79806 | 5-HT2A&5-HT2C agonist-1 | 5-HT Receptor | |
5-HT2A&5-HT2C agonist-1 (Example 2) is a dual-acting agent targeting the 5-HT2A and 5-HT2C receptors with respective IC50 values of 196 nM and 0.9 nM. It is applicable in the study of various central nervous system disor... | |||
T79804 | 5-HT2 agonist-1 | 5-HT Receptor | |
Compound 24, a 5-HT2 agonist-1, selectively activates 5-HT2A, 5-HT2B, and 5-HT2C receptors with IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively. The free base form of this compound is utilized in research pertaini... |