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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2028 | NG 52 | NG52,NG-52,Compound 52 | CDK |
NG 52 (NG-52) is a cell-permeable, reversible, and ATP-compatible inhibitor of the cell cycle-regulating kinase Cdc28p and the related Pho85p kinase. | |||
T1801 | SR9243 | Liver X Receptor | |
SR9243, an LXR inverse agonist, can induce LXR-corepressor interaction; shows anticancer activity and selectively targets the lipogenesis and Warburg effect. | |||
T62758 | PKM2 activator 2 | PKM | |
PKM2 activator 2 is a pyruvate kinase M2 (PKM2) activator with an AC 50 value of 66 nM.PKM2 activator 2 has anti-tumor proliferative properties and attenuates the Warburg effect by normalizing cellular glycolytic metabol... | |||
T17224 | VER-246608 | Dehydrogenase , PDK | |
VER-246608 is an effective and ATP-competitive inhibitor of pyruvate dehydrogenase kinase (IC50s: 35 nM, 40 nM, 84 nM, and 91 nM for PDK-1, PDK-3, PDK-2, and PDK-4, respectively).VER-246608 disrupts Warburg metabolism an... | |||
T79369 | ZMF-23 | PAK | |
ZMF-23, a PAK1/HDAC6 dual inhibitor, suppresses PAK1 and HDAC6-mediated aerobic glycolysis and cellular migration while inducing TNF-α-regulated necroptosis and augmenting apoptosis. The compound effectively hampers the ... |