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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP2071L | Bay 55-9837 acetate | Glucagon Receptor | |
Bay 55-9837 acetate is a potent and highly selective VPAC2 agonist(Kd = 0.65 nM) and can be used in type 2 diabetes studies. | |||
T41005 | PA-8 | PACAP | |
PA-8 is a small molecule receptor antagonist for PACAP Type I (PAC1) that is selective, effective, and orally active. PA-8 inhibits PacAP-induced CREB phosphorylation at PAC1- receptors, but does not inhibit VPAC1- or vp... | |||
TP2071 | Bay 55-9837 | ||
Selective VPAC2 receptor agonist (EC50 values are 0.4, 100 and >1000 nM for VPAC2, VPAC1 and PAC1, respectively in a cAMP accumulation assay; IC50 values are 60, 8700 and >10000 nM for VPAC2, VPAC1 and PAC1, respectively... | |||
T81727 | Myristoyl-(Lys12,27,28)-VIP-Gly-Gly-Thr free acid | ||
Myristoyl-(Lys12,27,28)-VIP-Gly-Gly-Thr (free acid) serves as a selective and potent antagonist of the VPAC2 receptor [1]. | |||
T80876 | Vasomera | ||
Vasomera, a stable, long-acting vasoactive intestinal peptide (VIP) agonist, targets G-protein-coupled VPAC2 receptors and is employed in the study of cardiomyopathy associated with dystrophinopathies [1]. | |||
T75825 | Bay 55-9837 TFA | ||
Bay 55-9837 TFA, a potent and highly selective VPAC2 agonist with a dissociation constant (Kd) of 0.65 nM, represents a potential research therapy for type 2 diabetes [1]. | |||
TP1069 | PACAP (1-27), human, ovine, rat TFA | PACAP 1-27 TFA | |
PACAP (1-27), human, ovine, rat TFA (PACAP 1-27 TFA) is an N-terminal fragment of pacap-38 and an effective PACAP receptor antagonist. The IC50s for rat PAC1, rat VPAC1 and human VPAC2 are 3nm, 2nm and 5nm respectively. | |||
T36427 | PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt) | PACAP | |
Pituitary adenylate cyclase-activating peptide (PACAP) (6-27) is a PACAP receptor antagonist with IC50 values of 1,500, 600, and 300 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors expres... |
Cat No. | Product Name | Species | Expression System |
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TMPY-01120 | VPAC2 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
VIP and PACAP receptor 2, or VIPR2 encodes the VPAC2 receptor, which binds both VIP and PACAP. VPAC2 is expressed throughout the central nervous system and the periphery. Mutations in the VIPR2 homolog in the mouse cause... | |||
TMPY-03597 | VIP Protein, Human, Recombinant (His) | Human | HEK293 Cells |
VIP, or vasoactive intestinal peptide, is a neuropeptide of 28 amino acid residues that belongs to a glucagon/secretin superfamily, and it exerts its actions through three G-protein-coupled receptors (PAC1, VPAC1, and VP... |