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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T73234 | USP7-IN-7 | ||
USP7-IN-7, a potent USP7 inhibitor, exhibits an IC50 value of <10 nM. Demonstrating cytotoxicity against both p53-mutant and p53 wild-type blood cancer, as well as neuroblastoma cell lines at low nanomolar concentrations... | |||
T13268 | USP7-IN-1 | DUB | |
USP7-IN-1 is a selective and reversible ubiquitin-specific protease 7 (USP7) inhibitor (IC50 = 77 μM). | |||
T9217 | USP7-IN-8 | GNE-6776 | DUB |
Benzamide, 4-[6-amino-4-ethyl-5-(4-hydroxyphenyl)-3-pyridinyl]-N-methyl- is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM. USP7-IN-8 (GNE-6776) has anticancer effects. | |||
T13271 | USP7-IN-6 | DUB | |
USP7-IN-6 is a potent inhibitor of ubiquitin-specific protease 7 (USP7, IC50: 6.8 nM). | |||
T13269 | USP7-IN-3 | DUB | |
USP7-IN-3 is a potent and selective allosteric inhibitor of ubiquitin-specific protease 7 (USP7). | |||
T13270 | USP7-IN-5 | DUB | |
USP7-IN-5 is a potent inhibitor of ubiquitin-specific protease 7 (USP7, IC50: 49.9 nM). | |||
T21527 | HBX 41108 | HBX-41108 | DUB , p53 |
HBX 41108 (HBX-41108) is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBX 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM. | |||
T78150 | USP7-IN-10 hydrochloride | ||
USP7-IN-10 hydrochloride, also known as compound 1, is a potent inhibitor of the enzyme ubiquitin-specific protease 7 (USP7), exhibiting an IC50 value of 13.39 nM [1]. | |||
T73136 | USP7-IN-10 | ||
USP7-IN-10 is a potent inhibitor of ubiquitin-specific protease 7 (USP7), exhibiting an inhibition concentration half-maximal (IC50) value of 13.39 nM. | |||
T73257 | USP7-IN-9 | ||
USP7-IN-9, a potent inhibitor of ubiquitin-specific protease 7 (USP7) with an IC50 of 40.8 nM, effectively induces apoptosis and arrests cell progression at the G0/G1 and S phases in RS4;11 cells. It decreases the protei... | |||
T74682 | U7D-1 | PROTACs | |
U7D-1, a groundbreaking and selective ubiquitin-specific protease 7 (USP7) PROTAC degrader, exhibits a DC50 value of 33 nM in RS4;11 cells, demonstrating its potent anticancer properties. Furthermore, U7D-1 effectively i... |