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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1649 | Tenofovir | PMPA,TDF,GS 1278 | HBV , HIV Protease , Reverse Transcriptase |
Tenofovir (GS 1278) is an adenine analog REVERSE TRANSC-RIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B. It is used to treat HIV INFECTIONS and CHRONIC HEPATITIS B, in combination with other ANTIV... | |||
T28946 | Tenofovir exalidex | Tenofovir,HDP-Tenofovir,CMX-157,CMX157,CMX 157 | Antiviral |
Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistant HIV strains, including those resistant to multiple nucleosi... | |||
T7282 | Tenofovir alafenamide hemifumarate | GS-7340 (hemifumarate),Tenofovir alafenamide fumarate | HIV Protease , Reverse Transcriptase |
Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an oral phosphonoamidate prodrug of the HIV reverse transcriptase nucleotide inhibitor tenofovir (TFV) | |||
T2409L | Tenofovir Disoproxil Fumarate | GS-1278 Disoproxil Fumarate,Tenofovir DF | HBV , HIV Protease , Reverse Transcriptase |
Tenofovir Disoproxil Fumarate (GS-1278 Disoproxil Fumarate) is a pro-drug, fumaric acid salt form of tenofovir, a nucleoside reverse transcriptase inhibitor analog of adenosine. Tenofovir disoproxil fumarate is prescribe... | |||
T39043 | Tenofovir amibufenamide | HS-10234 | HBV |
Tenofovir amibufenamide (HS-10234) (HS-10234) is a Tenofovir prodrug, an antiviral compound with oral activity. Tenofovir amibufenamide inhibits hepatitis B virus (HBV) and can be used in chronic hepatitis B (CHB) studie... | |||
T12814 | (S)-Tenofovir | (S)-PMPA,(S)-GS 1278,(S)-TDF | Others |
(S)-Tenofovir ((S)-PMPA) is the less active S-enantiomer of Tenofovir which is a nucleotide reverse transcriptase inhibitor. | |||
T41249 | Tenofovir alafenamide fumarate | GS-7340 fumarate | HIV Protease |
Tenofovir alafenamide fumarate (GS-7340 fumarate) is an orally available Tenofovir precursor compound Tenofovir alafenamide fumarate has anti-HIV activity and can be used to prevent HIV infection. | |||
T2409 | Tenofovir alafenamide | GS-7340 | HIV Protease , Reverse Transcriptase |
Tenofovir alafenamide (GS-7340) is a nucleotide reverse transcriptase inhibitor (NRTI) and a novel ester prodrug of the antiretroviral tenofovir. | |||
T7111 | Tenofovir Disoproxil | GS 4331,Bis(POC)-PMPA | HBV , HIV Protease , Reverse Transcriptase |
Tenofovir Disoproxil (GS 4331) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. | |||
T63290 | (R,1R)-Tenofovir amibufenamide | (R,1R)-HS-10234 | Antiviral |
(R,1R)-Tenofovir amibufenamide ((R,1R)-HS-10234) can be used as a Tenofovir prodrug, which can be taken orally and has antiviral activity. Tynofovir is a nucleotide reverse transcriptase inhibitor. | |||
T40238 | Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium | Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium | |
Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) displays a prolonged half-life (t1/2) compared to tenofovir in human liver microsomes. Moreover, it demonstrates potent in vitro anti-HIV activity and improves in viv... | |||
T40239 | Tenofovir-C3-O-C15-CF3 ammonium | Tenofovir-C3-O-C15-CF3 ammonium | |
Tenofovir-C3-O-C15-CF3 (ammonium) demonstrates prolonged half-life values compared to tenofovir in human liver microsomes. It exhibits potent anti-HIV activity in vitro and enhances pharmacokinetic properties in vivo. | |||
T37909 | Tenofovir diphosphate | ||
Tenofovir diphosphate (TFV-DP) is a competitive inhibitor of DNA polymerases, specifically targeting dATP, and it serves as a substrate for the reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1)[1]... | |||
T37910 | Tenofovir diphosphate triethylamine | ||
Tenofovir diphosphate triethylamine (TFV-DP triethylamine) is a competitive inhibitor of DNA polymerases for dATP, functioning as a substrate for HIV type 1 reverse transcriptase (HIV-1 RT)[1]. | |||
T37523 | Tenofovir diphosphate (sodium salt) | ||
Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase (Kis = 0.022 and 1.55 μM for RNA and DNA, respectively) and hepatitis B virus (HBV) polymerase (Ki = 0.18 μM). It is selective for these enzymes over DNA... | |||
T21775 | Tenofovir maleate | ||
Tenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor used in the treatment of HIV and chronic Hepatitis B. | |||
T1649L | Tenofovir hydrate | ||
Tenofovir hydrate is a nucleotide reverse transcriptase inhibitor used in the treatment of HIV and chronic Hepatitis B. | |||
T28945 | Tenofovir disoproxil aspartate | CKD-390,CKD390,CKD 390 | |
Tenofovir disoproxil aspartate, a nucleotide reverse transcriptase inhibitor, is used potentially for the treatment of HBV infection. | |||
T12127 | 9-Propenyladenine | Mutagenic Impurity of Tenofovir Disoproxil,Tenofovir Impurity 2 | Others |
9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. | |||
T13457 | (Z)-9-Propenyladenine | (Z)-Mutagenic Impurity of Tenofovir Disoproxil | Others |
(Z)-9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. |