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Search Results for " tnk2 "

11

Compounds

Cat No. Product Name Synonyms Targets
T62164 TNK2-IN-1
TNK2-IN-1 is a TNK2 inhibitor (IC50: 224 nM) that can be used in cancer research.
T5092 AIM-100 AIM100 ACK
AIM-100 is a Ack1 inhibitor (IC50: 24 nM).
T3196 GNF-7 GNF7 Bcr-Abl , ACK , AChR
GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respectively.
T2641 KRCA-0008 KRCA 0008,KRCA0008 ACK , ALK
KRCA-0008 is an effective and specific ALK/Ack1 inhibitor (IC50: 12/4 nM); displays drug-like properties without hERG liability.
T3710 XMD16-5 Tyrosinase , PPAR
XMD16-5 is a TNK2 inhibitor. TNK2 genomic amplification has been associated with late-stage or metastatic lung and prostate Ys. Overexpression of TNK2 promoted metastasis in a mouse model of breast Y. TNK2 signaling is d...
T3709 XMD8-87 ACK1-B19 Tyrosinase , PPAR
XMD8-87 (ACK1-B19) is a TNK2 inhibitor with activity in the inhibition of TNK2 phosphorylation. XMD8-87 and XMD16-5 potently inhibit phosphorylation of TNK2 truncation mutations found in solid tumor types.
T3630 Relugolix RVT-601,TAK-385 GNRH Receptor
Relugolix (RVT-601) is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, with potential antineoplastic activity. Relugolix competitively bi...
T74642 DB1113
DB1113 (Example 24) is a bifunctional compound designed for the targeted degradation of various kinases. It effectively degrades a range of kinases, including ABL1, ABL2, BLK, CDK11B, CDK4, CSK, EPHA3, FER, GAK, LIMK1, M...
T82385 FMF-06-098-1 PROTACs
FMF-06-098-1 is a multitargeted depressant capable of promoting the degradation of a wide array of kinases, including AAK1, ABL2, AURKA, AURKB, BUB1B, CDC7, CDK1, CDK12, CDK13, CDK2, CDK4, CDK6, CDK7, CDK9, CHEK1, CSNK1D...
T74644 DB0614
DB0614 (Example 21) is a bifunctional compound designed for the targeted degradation of kinases, effectively breaking down a wide array of kinases including AAK1, AURKA, BMP2K, CAMKK1, CDK16, CML, CDK6, EIF2AK2, FER, GAK...
T12102 Mps1-IN-1 Others
Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM )
TargetMol