tlr7 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4258	TLR7 agonist 2	TLR7-agonist-1,TLR7-IN-1	TLR
	TLR7 agonist 2 (TLR7-IN-1) is a specific and effective Toll-like Receptor 7 (TLR7) agonist (LEC=0.4 μM).		TLR
T5561	TLR7/8 agonist 1 dihydrochloride	TLR7/8 agonist-5d	TLR
	TLR7/8 agonist 1 dihydrochloride (TLR7/8 agonist-5d) is a TLR7/8 agonist which shows prominent immunostimulatory activities.		TLR
T39669	TLR7/8/9-IN-1	TLR7/8/9-IN-1	TLR
	TLR7/8/9-IN-1 is a potent inhibitor of Toll-like receptors 7/8/9 (TLR7/8/9) with an IC50 of 43 nM.		TLR
T38078	TLR7/8-IN-1	TLR7/8-IN-1	TLR
	TLR7/8-IN-1, a crystalline TLR7/TLR8 inhibitor, is a valuable compound for autoimmune disease research[1].		TLR
T13167	TLR7/8 agonist 3		TLR
	TLR7/8 agonist 3 is a potent agonist of TLR7 and TLR8.		TLR
T8316	1V209	TLR7 agonist T7	TLR
	1V209 (TLR7 agonist T7) is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects.		TLR
T39970	TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride	TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride
	TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) is a drug-linker conjugate used in antibody-drug conjugates (ADCs) with high efficacy against tumors. It consists of TLR7/8 agonist 4, a potent TLR7/8 agonis...
T38614	TLR7 agonist 3
	TLR7 agonist 3 (Compound 2), a potent activator of toll-like receptor 7 (TLR7), plays a critical role in initiating immune responses, positioning it as a promising target for immunomodulator development.
T39968	TLR7/8 agonist 4 hydroxy-PEG10-acid	TLR7/8 agonist 4 hydroxy-PEG10-acid
	TLR7/8 agonist 4 hydroxy-PEG10-acid (compound 9) is a drug-linker conjugate employed in antibody-drug conjugates (ADC). This compound exhibits remarkable antitumor activity by utilizing TLR7/8 agonist 4, which acts as a ...
T13168	TLR7 agonist 1		TLR
	TLR7 agonist 1 is a selective and oral TLR7 agonist (IC50: 90 nM).		TLR
T39969	TLR7/8 agonist 4 TFA
	TLR7/8 agonist 4 TFA (compound 41) is a highly potent TLR7/8 agonist that exhibits significant anti-cancer activity.
T72035	TLR7/8/9 antagonist 2		TLR
	TLR7/8/9 antagonist 2 is an orally active and highly bioavailable vTLR7/8/9 antagonist. TLR7/8/9 antagonist 2 inhibits HEK/hTLR7, HEK/hTLR8 and HEK/hTLR9 with IC50s of 0.011 μM, 0.029 μM and 0,052 μM, respectively. TLR7/...		TLR
T71108	TLR7/8 agonist 1
	TLR7/8 agonist 1 is a toll-like receptor ( TLR7 )/ TLR8 dual-agonistic imidazoquinoline.
T62587	TLR7 agonist 4
	TLR7 agonist 4 (Compound 1.2) is a TLR7 agonist (EC50: 4.3 nM).
TNU1350	TLR7 agonist 13
	TLR7 agonist 13 is a useful organic compound for research related to life sciences. The catalog number is TNU1350 and the CAS number is 2389988-70-7.
T79751	TLR7 agonist 16
	TLR7 agonist 16 (compound 16d) is a potent activator of TLR7 with an EC50 value of 18 nM. It effectively triggers the activation of both mouse macrophages and human peripheral blood mononuclear cells (hPBMCs) at low-nano...
T79750	TLR7 agonist 15
	TLR7 agonist 15 (compound 16b) is a potent activator of mouse macrophages and hPBMCs, demonstrating an EC50 of 18 nM. It induces robust responses at low-nanomolar concentrations [1].
T79749	TLR7 agonist 14
	Compound 17b, a TLR7 agonist also known as TLR7 agonist 14, exhibits high potency with an EC50 of 18 nM. It effectively activates mouse macrophages and human peripheral blood mononuclear cells (hPBMCs) at low-nanomolar c...
T75213	TLR7 agonist 12
	TLR7 agonist 12 (example 20), a purine nucleoside analog, functions as a TLR7 agonist with broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include DNA synthesis in...
T79068	TLR7/8 agonist 8
	TLR7/8 agonist 8 (compound 24m) is a potent dual agonist for toll-like receptors 7 and 8 (TLR7/8), exhibiting half-maximal effective concentrations (EC50s) of 27 nM for human TLR7 (hTLR7) and 12 nM for human TLR8 (hTLR8)...