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Search Results for " sirtuin-3 "

12

Compounds

Cat No. Product Name Synonyms Targets
T21679 4'-bromo-Resveratrol Sirtuin
4'-bromo-Resveratrolis a potent inhibitor of the deacetylases sirtuin 1 (SIRT1) and 3 (SIRT3)
T9999 Sirtuin modulator 2 N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide Others , Sirtuin
Sirtuin modulator 2 (N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide) exhibits antidiabetic, anti-inflammatory and antitumor activities.
T4108 3-TYP 3-(1H-1,2,3-triazol-4-yl) pyridine Sirtuin
3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor.
T9998 MIND4-19 Sirtuin
MIND4-19 is an inhibitor of SIRT2 with antitumor activity.
T9320 YK-3-237 B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid Sirtuin
YK-3-237 (B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid) reduces acetylation of mtp53 and exhibits anti-proliferative effects toward triple-negative breast cancer (TNBC) cells ca...
T6371 AGK2 Apoptosis , Sirtuin
AGK2(IC50=3.5 μM) is an effective, and specific SIRT2 inhibitor.
T5096 SRT 1720 Sirtuin , Autophagy
SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.
T8346 SRT 1460 SRT1460 Sirtuin
SRT 1460 is a SIRT1 activator.
T60001 Benzamide, 3-methoxy-N-(3-thiazolo[5,4-b]pyridin-2-ylphenyl) 3-methoxy-N-(3-(thiazolo[5,4-b]pyridin-2-yl)phenyl)benzamide Sirtuin
Benzamide, 3-methoxy-N-(3-thiazolo[5,4-b]pyridin-2-ylphenyl) (3-methoxy-N-(3-(thiazolo[5,4-b]pyridin-2-yl)phenyl)benzamide) is a sirtuin modulator and useful for increasing the lifespan of a cell, and treating and/or pre...
T35821 CAY10721
CAY10721 is an inhibitor of sirtuin 3 (SIRT3), a class III HDAC (39% SIRT3 inhibition at 200 μM). Upregulation of SIRT3 transcription is associated with oral squamous cell carcinoma (OSCC) and breast cancer with lymph no...
T35822 CAY10722
CAY10722 is an inhibitor of sirtuin 3 (SIRT3), a class III HDAC (71% inhibition at 200 μM). SIRT3 is involved in modulating metabolic homeostasis as a NAD+-dependent protein deacetylase in the mitochondria. SIRT3 functio...
T36521 Alaproclate (hydrochloride)
Alaproclate is a selective serotonin reuptake inhibitor (SSRI).1,2 It inhibits depletion of serotonin (5-HT) induced by 4-methyl-α-ethyl-m-tyramine in rat cerebral cortex, hippocampus, hypothalamus, and striatum (EC50s =...
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