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Search Results for " scc "

Targets

8

Compounds

1

Natural Products

8

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T5414 Glumetinib SCC244 c-Met/HGFR
Glumetinib (SCC244) (SCC 244) is a novel potent and selective inhibitor of c-Met kinase (IC50: 0.42 nM).
T26889 Borofalan(10B) L-4-Boronophenylalanine Others
Borofalan(10B) (L-4-Boronophenylalanine) echibits antineoplastic effects. Borofalan can be used in studies on recurrent or locally advanced head and neck cancer.
T82324 GGASCCLYCRCH
GGASCCLYCRCH is a bioactive peptide that can inhibit the 2-O-methyltransferase activity within the SARS-CoV nsp16/10 complex.
T19552 RPH-2823 Others
RPH-2823, a basic amphotericin analog, is diuretic, natriuretic, and potassium-preserving, inducing a dose-dependent decrease in SCC and an increase in trans-epithelial resistance.
T36865 Heat Shock Protein Inhibitor II
Heat shock protein (Hsp) inhibitor II is the active form of Hsp inhibitor I and a benzylidene lactam compound that prevents the synthesis of inducible Hsps, such as Hsp105, Hsp72, and Hsp40. Hsp inhibitor II decreases Hs...
T35810 C24 dihydro Ceramide (d18:0/24:0) Cer(d18:0/24:0)
C24 dihydro Ceramide is a sphingolipid that has been found in the stratum corneum of human skin.[1] It is found in higher concentrations in female sebum compared to male sebum.[2] C24 dihydro Ceramide levels positively c...
T36846 Chromomycin A2
Chromomycin A2 is an aureolic acid that has been found in several marine actinomycetes and has antibacterial and anticancer activities. Chromomycin A2 inhibits the growth of B. subtilis in an agar diffusion assay. It als...
T35426 β-Defensin-1 (human) (trifluoroacetate salt)
β-Defensin-1 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth ofB. adolescentis,L. acidophilus...
Cat No. Product Name Synonyms Targets
T6116 Bleomycin Sulfate Blenoxane,NSC125066 DNA/RNA Synthesis , Antibiotic
Bleomycin Sulfate (Blenoxane) is a glycopeptide antibiotic, an inhibitor of DNA synthesis. Bleomycin Sulfate causes DNA strand breaks but not RNA strand breaks. Bleomycin Sulfate has antitumor activity.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02712 Serpin B3 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
SERPINB3, also known as SCCA-1, belongs to the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was orig...
TMPY-03416 TNFAIP8 Protein, Human, Recombinant (His) Human E. coli
Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8) family is a newly identified protein with vital roles in maintaining immune homeostasis. Tumor necrosis factor-alpha-inducible protein 8 (TNFAIP8) is a TNF-al...
TMPH-01084 CYP11A1 Protein, Human, Recombinant (His & SUMO) Human E. coli
CYP11A1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 72.1 kDa and the accession number is P05108.
TMPY-02763 DEP-1 Protein, Human, Recombinant (aa 997-1337, His) Human E. coli
DEP1 / PTPRJ (Receptor-type tyrosine-protein phosphatase eta) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, includin...
TMPY-02766 PSPH Protein, Human, Recombinant Human E. coli
Phosphoserine phosphatase (PSPH) belongs to a subfamily of the phosphotransferases. PSPH is the rate-limiting enzyme in l-serine biosynthesis. It has previously been found that Phosphoserine phosphatase (PSPH) plays a ro...
TMPY-02391 SUMO1 Protein, Human, Recombinant (His) Human E. coli
Small ubiquitin-like modifier protein (SUMO) modification is a highly dynamic process, catalyzed by SUMO-specific activating (E1), conjugating (E2) and ligating (E3) enzymes, and reversed by a family of SUMO-specific pro...
TMPY-02511 PTP alpha/PTPRA Protein, Human, Recombinant (aa 174-793, His & GST) Human Baculovirus Insect Cells
PTPRA is reported to be involved in cancer development and progression through activating the Src family kinase (SFK) signaling pathways. The higher PTPRA level was associated with worse prognosis of SCC patients and PTP...
TMPY-03748 BCL2L12 Protein, Human, Recombinant (GST) Human E. coli
BCL2-like 12 (BCL2L12 ) is a new member of the apoptosis-related BCL2 gene family, members of which are implicated in various malignancies. The mRNA expression of BCL2L12 may constitute a novel biomarker for the predicti...
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