rp7 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP1932L1	[D-Trp7,9,10]-Substance P acetate		Others
	[D-Trp7,9,10]-Substance P acetate is an analogue of substance P which inhibits ion conductance through nicotinic acetylcholine receptors.		Others
T67897	GRP78-IN-3		HSP
	GRP78-IN-3, a potent small-molecule-competitive inhibitor of Hsp70 substrate binding and is a selective Grp78 (HSPA5) inhibitor with an IC50 of 0.59 μM. GRP78-IN-3 is 7-fold selective for HspA5 compared to HspA9 (IC50 of...		HSP
TP1931L1	[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate	[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate(96736-12-8 free base)	cholecystokinin
	[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate ([D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate (96736-12-8 free base)) is a broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist ...		cholecystokinin
T73025	PARP7-IN-12
	PARP7-IN-12, a potent inhibitor targeting PARP7, exhibits an IC50 of 7.836 nM. This compound is applicable in cancer research.
T76407	[D-Pro2,D-Trp7,9] Substance P
	[D-Pro2,D-Trp7,9] Substance P, an analogue of Substance P, functions both as a weak agonist and as a potent, specific, competitive antagonist to Substance P [1] [2].
T34215	QF-Erp7	QF Erp7,Abz-G-G-F-L-R-R-V-eddn
	QF-Erp7 is a novel quenched fluorescence substrate structurally related to enkephalin.
T76635	(Trp7,β-Ala8)-Neurokinin A (4-10)
	(Trp7,β-Ala8)-Neurokinin A (4-10) is a potent neurokinin-3 (NK3) antagonist [1] .
T75346	PARP7-probe-1
	PARP7-probe-1, a chemiluminescent-labeled and biotinylated probe, selectively binds to the PARP7 active site, facilitating research into PARP7 function [1].
T76406	[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11)
	[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) is a potent neurokinin NK1 antagonist that effectively inhibits the actions of gold-protein-substance P (GPSP) and substance P (SP), demonstrating its efficacy in neutralizing t...
T76445	(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P
	(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P is a neuropeptide Substance P antagonist [1] .
T81542	PARP7-IN-15		PARP
	PARP7-IN-15 (Compound 18) is a potent PARP7 inhibitor exhibiting an IC50 of 0.56 nM and demonstrates antitumor activity [1].		PARP
T63243	GRP78-IN-2
	GRP78-IN-2 is a glucose regulatory protein 78 (GRP78) inhibitor that preferentially targets GRP78 on the cell surface and has significant anti-angiogenic and anti-cancer effects without affecting other normal cells.
T28613	RP73870	RP 73870,RP-73870
	RP73870 is a gastrin/cholecystokinin-B receptor antagonist and H2 receptor antagonist with potent anti-ulcer activity.
T83495	[D-Pro4,D-Trp7,9] Substance P (4-11)
	[D-Pro4,D-Trp7,9] Substance P (4-11) acts as a potent antagonist to Substance P, significantly reducing plasma aldosterone (ALDO) concentrations[1].
T61106	GRP78-IN-1
	GRP78-IN-1 displays interactions with specific residues on the GRP78 protein with a binding energy of -8.07 kcal/mol. This compound possesses potent cytotoxic and anti-proliferative effects on cancer cells, particularly ...
T83548	(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P acetate
	(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P (acetate), an antagonist for Substance P and Bombesin, modulates ocular inflammatory responses triggered by antidromic trigeminal nerve stimulation [1].
TP1931	[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P
	Broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist for the ghrelin receptor (EC50 = 5.2 nM); diminishes constitutive ghrelin receptor signaling. Also antagonist at tachykinin, bradyki...
T81541	PARP7-IN-16		PARP
	PARP7-IN-16 (compound 36) is a potent, selective, and orally active PARP-1/2/7 inhibitor, exhibiting IC50 values of 0.94, 0.87, and 0.21 nM , respectively. It has potential applications in breast and prostate cancer rese...		PARP
TP1932	[D-Trp7,9,10]-Substance P
	Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.
T83496	[D-Pro4,D-Trp7,9,10] Substance P (4-11)
	[D-Pro4,D-Trp7,9,10] Substance P (4-11) serves as a potent antagonist of the tachykinin family of neuropeptides [1].

Compounds

[D-Trp7,9,10]-Substance P acetate

TP1932L1

[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate

TP1931L1

Synonym: [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate(96736-12-8 free base)

Target: cholecystokinin

[D-Pro2,D-Trp7,9] Substance P

Synonym: QF Erp7,Abz-G-G-F-L-R-R-V-eddn

Target:

(Trp7,β-Ala8)-Neurokinin A (4-10)

[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11)

T76406

Synonym:

Target:

(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P

Synonym: RP 73870,RP-73870

Target:

[D-Pro4,D-Trp7,9] Substance P (4-11)

(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P acetate

T83548

Synonym:

Target:

[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P

[D-Trp7,9,10]-Substance P

TP1932

Synonym:

Target:

[D-Pro4,D-Trp7,9,10] Substance P (4-11)

T83496

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-00142	ROM1 Protein, Human, Recombinant (His)	Human	E. coli
	ROM1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 18 kDa and the accession number is Q03395.
TMPY-03178	ERP72 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ERP72 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.6 kDa and the accession number is P13667.
TMPH-02111	SRP72 Protein, Human, Recombinant (GST)	Human	E. coli
	Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might intera...
TMPY-03177	ERP72 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	ERP72 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 97.2 kDa and the accession number is P13667.