4
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6120 | Pralatrexate | Folotyn,10-Propargyl-10-deazaaminopterin | Apoptosis , DHFR , Antifolate , TAM Receptor |
Pralatrexate (10-Propargyl-10-deazaaminopterin) is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive act... | |||
T25981 | Pralatrexate, (S)- | ||
Pralatrexate, (S)- is a folate analog dihydrofolate reductase (DHFR) inhibitor exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive activities. Pralatrexate selectively ... | |||
T25980 | Pralatrexate, (R)- | ||
Pralatrexate, (R)- is a folate analog dihydrofolate reductase (DHFR) inhibitor exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive activities. Pralatrexate selectively ... | |||
T73085 | Talotrexin | PT523 | |
Talotrexin (PT523), an analog of Aminopterin, is a nonpolyglutamatable classic antifolate that acts as a specific inhibitor of the reduced folate carrier (RFC). It selectively inhibits RFC transport, demonstrating antitu... |