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Search Results for " pr8 "

13

Compounds

Cat No. Product Name Synonyms Targets
T0994 Ketotifen fumarate HC 20511 fumarate PDE , Histamine Receptor
Ketotifen fumarate (HC 20511 fumarate) is a cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators.
T62656 GPR81 agonist 1 GPR
GPR81 agonist 1 is a potent and selective GPR81 agonist with high affinity for human and mouse GPR81.GPR81 agonist 1 inhibits lipolysis of differentiated 3T3-L1 adipocytes, improves insulin sensitivity and glycaemic cont...
T62261 GPR84 antagonist 1
GPR84 antagonist 1 is a highly selective, high-affinity competitive antagonist of human GPR84.
T11462 GPR84 antagonist 8 GPR
GPR84 antagonist 8 is a selective GPR84 antagonist.
T72536 GPR84 antagonist 2
GPR84 Antagonist 2, a potent and selective GPR84 antagonist (IC 50 = 8.95 nM), demonstrates oral activity and significantly enhances potency in calcium mobilization assays. It effectively inhibits neutrophil and macropha...
T72772 GPR81 agonist 2
GPR81 agonist 2 is a potent agonist targeting the GPR81 receptor, demonstrating EC50 values of 0.023 µM for hGPR81 and 0.123 µM for hGPR109A, respectively.
T62918 GPR84 antagonist 3
GPR84 Antagonist 3 (compound 42), a potent inhibitor of the G-protein-coupled receptor 84 (GPR84), exhibits a pIC50 value of 8.28, indicating strong antagonistic activity by inhibiting GTPγS. Additionally, it possesses a...
T79901 GPR88-IN-1
GPR88-IN-1 is a GPR88 antagonist that may be utilized for the study of central nervous system disorders [1].
T79902 GPR88 agonist 2
GPR88 agonist 2 (compound 53) serves as a potent, brain-penetrant agonist of GPR88, exhibiting an EC50 of 14 µM in the GPR88 cAMP functional assay [1].
T36739 Prednisone 21-aldehyde/22-hydroxy Prednisone
Prednisone 21-aldehyde is a derivative of the synthetic corticosteroid prednisone that has antiviral activity against influenza virus A-PR8 in embryonated chicken eggs. 22-hydroxy Prednisone is an unstable adduct of pred...
T37466 CAY10766
CAY10766 is an antiviral compound.1It inhibits entry of influenza virus-like particles pseudotyped with hemagglutinin A (HA) from H5N1 influenza A virus into A549 cells (EC50= 0.24 μM). CAY10766 (1 μM) reduces H1N1 and H...
T80279 Urumin Influenza Virus
Urumin, a compound with antiviral properties, inhibits human influenza A virus growth, particularly the PR8 strain, with an inhibitory concentration (IC 50) of 3.8 μM. It acts by targeting the conserved stalk of H1 hemag...
T15625 JNJ4796 Others
JNJ4796 is an oral active fusion inhibitor of the influenza virus, by inhibiting hemagglutinin (HA)-mediated fusion to neutralizing the influenza A group 1 virus. JNJ4796 mimics the functionality of the broadly neutraliz...
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