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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T20615 | Olsalazine | Dipentium,Salicylic acid | Others |
Olsalazine (Dipentium), an anti-inflammatory drug, is used in the treatment of inflammatory bowel disease. It is also a novel DNA hypomethylating agent. | |||
T22946 | LY255283 | LY 255283 | Leukotriene Receptor |
LY255283 is a specific antagonit of leukotriene B4 (LTB4) receptor. It inhibits the production of LTB(4) in human peripheral blood polymorphonuclear leukocytes (PMNL) and in monocytes activated by calcium ionophore A2318... | |||
T4114 | Diffractaic Acid | NSC 5901,NSC 685595 | Apoptosis , LTR |
Diffractaic Acid (NSC 685595) can inhibit LTB4 biosynthesis in A-23187-stimulated bovine PMNL cells with activity value of 8 μM. | |||
T37618 | Leukotriene B4 dimethyl amide | Leukotriene B4 dimethyl amide | |
LTB4 dimethyl amide is a moderate inhibitor of LTB4-induced degranulation of human neutrophils (Ki = 130 nM) and lysozyme release from rat PMNL. LTB4 dimethyl amide appears to be an antagonist of the LTB4 receptor on gui... | |||
T37400 | 15(S)-HETrE | ||
15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid . It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 μM. In RBL cells, 15(S)-HETrE inhibits 5-LO, but i... | |||
T37650 | 5(S),15(S)-DiHETE | ||
5(S),15(S)-DiHETE is synthesized by 15-LO from 5(S)-HETE. It potentiates the degranulation of human PMNL in response to PAF, but not fMLP, calcium ionophore A23187, or LTB4. 5(S),15(S)-DiHETE is chemotactic for eosinophi... | |||
T38087 | 20-hydroxy Leukotriene B4 | 20-hydroxy Leukotriene B4 | |
20-hydroxy LTB4 is a metabolite of LTB4 in human neutrophils. In human leukocytes, LTB4 is inactivated by the enzyme LTB4 20-hydroxylase. 20-hydroxy LTB4 is not only much less active (~5%) compared to LTB4 in causing deg... | |||
T37649 | 5(S),12(S)-DiHETE | ||
5(S),12(S)-DiHETE is a natural bioactive lipid derived from arachidonic acid . It is synthesized by glycogen-induced rabbit peritoneal polymorphonuclear leukocytes (PMNLs) incubated with AA. 5(S),12(S)-DiHETE can be prod... |