Powder: -20°C for 3 years | In solvent: -80°C for 1 year
5(S),12(S)-DiHETE is a natural bioactive lipid derived from arachidonic acid . It is synthesized by glycogen-induced rabbit peritoneal polymorphonuclear leukocytes (PMNLs) incubated with AA. 5(S),12(S)-DiHETE can be produced by successive oxygenation of AA by 5-lipoxygenase (5-LO) in platelets and 12-LO in leukocytes. It can also be synthesized from 12(S)-HETE by 5-LO, in the presence of 5-LO activating protein (FLAP), activated with calcium ionophore. 5(S),12(S)-DiHETE is an epimer of leukotriene B4 that is weakly chemotactic for PMNL.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 μg | 35 days | $ 396.00 | |
50 μg | 35 days | $ 765.00 | |
100 μg | 35 days | $ 1,440.00 |
Description | 5(S),12(S)-DiHETE is a natural bioactive lipid derived from arachidonic acid . It is synthesized by glycogen-induced rabbit peritoneal polymorphonuclear leukocytes (PMNLs) incubated with AA. 5(S),12(S)-DiHETE can be produced by successive oxygenation of AA by 5-lipoxygenase (5-LO) in platelets and 12-LO in leukocytes. It can also be synthesized from 12(S)-HETE by 5-LO, in the presence of 5-LO activating protein (FLAP), activated with calcium ionophore. 5(S),12(S)-DiHETE is an epimer of leukotriene B4 that is weakly chemotactic for PMNL. |
Molecular Weight | 336.472 |
Formula | C20H32O4 |
CAS No. | 79056-01-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: >50 mg/mL (per Rao Maddipati)
PBS (pH 7.2): >1 mg/mL (from 13(S)-HODE)
Ethanol: >50 mg/mL (per Rao Maddipati)
DMF: >50 mg/mL (per Rao Maddipati)
You can also refer to dose conversion for different animals. More
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5(S),12(S)-DiHETE 79056-01-2 5,12DiHETE 5(S),12(S) DiHETE 5(S),12(S)DiHETE inhibitor inhibit