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Search Results for " pl-pro "

Targets

5

Compounds

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T18911 Acriflavine Acriflavinium chloride 3,6-Acridinediamine mix SARS-CoV , Antibacterial
Acriflavine (Acriflavinium chloride 3,6-Acridinediamine mix) is a papain-like protease (PL(pro)) inhibitor, a fluorescent dye for labeling high molecular weight RNAs, has antimicrobial and anticancer activity, inhibits S...
T62991 Mpro/PLpro-IN-1
Mpro/PLpro-IN-1 (Compound 29) is a dual-acting inhibitor of SARS-CoV-2 protease.Mpro/PLpro-IN-1 is also a potent inhibitor of Mpro/PLpro, with micromolar inhibition of M pro (IC50:1.72 μM) and submicromolar inhibition of...
T81202 SARS-CoV-2-IN-69 SARS-CoV
SARS-CoV-2-IN-69 (Compound 7E) is a potent, non-covalent inhibitor of the SARS-CoV-2 main protease (M^pro) with an EC50 of 7.4 μM and also inhibits the papain-like protease (PL^pro) [1].
T61500 PLP_Snyder530
PLP_Snyder530 is a potent papain-like protease (PL pro ) inhibitor. PLP_Snyder530 induces conformational changes in SARS-COV-2 papain-like protease, inhibiting SARS-CoV-2 replication. PLP_Snyder530 can be used for SARS-C...
T75065 Antiviral agent 25
Antiviral agent 25 (compound 6g), a novel non-peptide analog covalent inhibitor of SARS-CoV-2 3CL pro, exhibits robust inhibitory activity against both SARS-CoV-2 3CL pro and SARS-CoV-2 PL pro, with IC50 values of 0.118 ...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPK-01352 SARS-CoV-2 PLpro/papain-like protease Protein (His & Avi) SARS E. coli
The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro ...
TMPK-01384 SARS PLpro/papain-like protease Protein (His) SARS E. coli
The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro ...
TMPJ-01431 SARS-CoV-2 Papain-Like Protease Protein SARS-CoV-2 E. coli
Replication of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) requires proteolytic processing of the replicase polyprotein by two viral cysteine proteases, a chymotrypsin-like protease (3CLpro) and a pap...
TargetMol