o-glcnac — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T16409	OSMI-1		Others , Acyltransferase
	OSMI-1 is an O-GlcNAc transferase (OGT) inhibitor (IC50=2.7 μM) that is orally active and cell-permeable. OSMI-1 inhibits protein O-GlcNA acetylation without qualitatively altering cell-surface N- or O- linked glycans.		Others , Acyltransferase
T75685	UDP-3-O-acyl-GlcNAc
	UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine), an E. coli metabolite, plays a role in the 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway [1].
T80020	UDP-3-O-acyl-GlcNAc diammonium	UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine diammonium	Endogenous Metabolite
	UDP-3-O-acyl-GlcNAc diammonium serves as a metabolite in E. coli, playing a critical role in the biosynthesis pathway of 3-deoxy-D-manno-octulosonate (KDO) [1].		Endogenous Metabolite
T38722	(Z)-PUGNAc		Others
	(Z)-PUGNAc is a potent O-GlcNAcase inhibitor that is more active than (E)-PUGNAc, removes O-GlcNAc from proteins (peptide O-GlcNAc-β-N-acetylaminoglucosidase), and can be used to increase the levels of O-GlcNAc on nuclea...		Others
T67760	JNJ-65355394		Others
	JNJ-65355394 is an effective O-GlcNAc hydrolase (OGA) inhibitor and an OGA chemical probe.		Others
T9190	NAG-thiazoline	GlcNAc-thiazoline	Others
	NAG-thiazoline (GlcNAc-thiazoline) is an O-GlcNAcase inhibitor with Ki value of 180 nM. It is active against V. campbellii with MIC value of 0.5 μM.		Others
T12327	OSMI-3		Others
	OSMI-3 is a potent and cell-permeable inhibitor of O-GlcNAc transferase (OGT) for the study of cancer and cardiovascular disease.		Others
T12328	OSMI-4		Others
	OSMI-4 is a low nanomolar O-GlcNAc transferase (OGT) inhibitor (EC50 of 3 μM in cells), which can be used to study OGT inhibition in different human cell lines.		Others
T19596	UDP-GlcNAc Disodium Salt	Uridine 5′-diphospho-N-acetylglucosamine,UDP-α-D-N-Acetylglucosamine Disodium Salt	Others
	UDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) is a nucleotide sugar. It is synthesized from glucose via the hexosamine biosynthetic pathway (HBP).		Others
T4514	N-Acetyl-D-Glucosamine	NAG,N-Acetyl-2-amino-2-deoxyglucose,Marine Sweet,N-Acetyl-2-amino-2-deoxy-D-glucose,GlcNAc	Endogenous Metabolite
	N-Acetyl-D-Glucosamine (NAG) is a monosaccharide derivative of glucose. It is released by the action of O-GlcNAcase, in mammalian systems from proteins that have been post-translationally modified with O-GlcNAc.		Endogenous Metabolite
T6056	Thiamet G	TMG	Others , Autophagy
	Thiamet G is a potent, selective O-GlcNAcase inhibitor with Kiof 21 nM, while exhibiting 37, 000-fold selectivity over human lysosomal –hexosaminidase.		Others , Autophagy
T9711	OGT-IN-2		Others
	OGT-IN-2 is a potent O-GlcNAc transferase (OGT) inhibitor. OGT-IN-2 inhibits sOGT and ncOGT with IC50 values of 30 μM and 53 μM, respectively[1]. OGT-IN-2 can be used for the research of articular diseases[1].		Others
T69343	BZX1
	BZX1 is a novel inhibitor of O-GlcNAc transferase (OGT) activity.
T74160	UDP-glucosamine disodium
	UDP-glucosamine (UDP-GlcNAc) disodium serves as a substrate for O-GlcNAc transferase, facilitating the addition of O-GlcNAc to proteins, while its removal is catalyzed by O-GlcNAcase. This compound also represents the cu...
T71958	BZX2
	BZX2 is a novel inhibitor of O-GlcNAc transferase (OGT) activity.
T63871	PG 34
	PG 34 is a structural analogue of OSMI-1 and a weak inhibitor of O-GlcNAc translocase (OGT) with an IC50 value of 68 μM.
T63988	(Rac)-OSMI-1
	(Rac)-OSMI-1 is a racemate of OSMI-1. OSMI-1 is an inhibitor of O-GlcNAc transferase (OGT) (IC50: 2.7 μM). OSMI-1 inhibits protein O-linked N-acetylglucosaminoglycans (O-GlcNAcylation) in mammalian cell lines and does no...
T36577	K-Biotin-W-Histone H2B (108-125) (trifluoroacetate salt)	K-Biotin-W-Histone H2B (108-125) (trifluoroacetate salt)
	Histone H2B (108-125) is a peptide fragment of histone H2B that corresponds to amino acid residues 109-126 of the human histone H2B sequence. It contains an N-terminal biotinylated lysine followed by a tryptophan linker....