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Search Results for " notum "

7

Compounds

Cat No. Product Name Synonyms Targets
T60057 Notum pectinacetylesterase-1 Others
Notum pectinacetylesterase-1 is a Notum Pectinacetylesterase inhibitor with IC50 < 0.025 μM.
T73212 Notum-IN-1
Notum-IN-1 is an orally administered, selective, and brain-penetrating compound that acts as an inhibitor of Notum. It effectively inhibits Wnt signaling in vivo in mice.
T38776 LP-922056 Wnt/beta-catenin
LP-922056 is an inhibitor of Notum Pectinacetylesterase with EC50 values of 21 nM, 55 nM for human and mouse, respectively.
T77524 Carboxylesterase-IN-2 Wnt/beta-catenin , Lipid
Carboxylesterase-IN-2 is a potent Carboxylesterase Notum inhibitor (IC50 <= 10 nM).Carboxylesterase-IN-2 has potential for the study of cancer diseases.
T23602 ABC99 ABC 99,ABC-99 Wnt/beta-catenin
ABC99 is a selective irreversible inhibitor of the wnt-deacylating enzyme. ABC99 inhibited NOTUM (IC50: 13 nM). It also showed excellent selectivity across the serine hydrolase family.
T60788 Carboxylesterase-IN-3 Wnt/beta-catenin , Lipid
Carboxylesterase-IN-3 is a potent inhibitor of Carboxylesterase Notum (IC50 ≤ 10 nM).Carboxylesterase-IN-3 has the potential to study cancer diseases.
T60537 ARUK3001185
ARUK3001185 (Compound 8l) is a potent, selective, orally active, and brain-penetrant Notum inhibitor(IC50 = 6.7 nM) that is suitable for oral dosing in rodent models of disease [1].
TargetMol