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Search Results for " neprilysin "

18

Compounds

Cat No. Product Name Synonyms Targets
T7693 Thiorphan Neprilysin
Thiorphan is an neprilysin inhibitor (NEP; IC50 : 0.007 μM).
T1176 Racecadotril Acetorphan Neprilysin , Proteasome
Racecadotril (Acetorphan) has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and Acute Gastroenteritis.
TQ0106 Sacubitrilat LBQ-657 Neprilysin
Sacubitrilat (LBQ-657) (LBQ657) is an effective inhibitor of active neprilysin (NEP).
T2318 Sacubitril/Valsartan Sacubitril mixture with Valsartan,Valsartan,Sacubitril,LCZ696 Apoptosis , RAAS , Neprilysin
Sacubitril/Valsartan (LCZ696) is an orally bioavailable, dual angiotensin II receptor and neprilysin inhibitor for the treatment of hypertension and heart failure.
T4574 Sacubitril AHU 377,AHU377,AHU-377 Neprilysin
Sacubitril (AHU-377) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril is a component of the heart failure medicine LCZ696.
T4200 Sacubitril hemicalcium salt AHU-377 (hemicalcium salt),AHU377 calcium salt Neprilysin
Sacubitril hemicalcium salt (AHU377 calcium salt) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril hemicalcium salt is a component of the heart failure medicine LCZ696. Sacubitril hemicalcium salt is a prodrug ...
TP2045 CH 275
Potent somatostatin receptor 1 (sst1) agonist; displays selectivity for sst1 (IC50 values are 30.9 nM, 345 nM, > 1 μM, > 10 μM and > 10μM for human sst1, sst3, sst4, sst2 and sst5 respectively). Attenuates somatostatin r...
T6627 Phosphoramidon Disodium Phosphoramidon Disodium Salt RAAS , Neprilysin , Others
Phosphoramidon Disodium (Phosphoramidon Disodium Salt) Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool.
T19112L Sacubitril Enantiomer 2R,4S-Sacubitril,ahu377 isomer 2 Others
Sacubitril Enantiomer (ahu377 isomer 2) is the enantiomer of Sacubitril which is a neprilysin inhibitor.
T19114L Sacubitril-(2S,4S)-Isomer (2S,4S)-Sacubitril Others
Sacubitril-(2S,4S)-Isomer ((2S,4S)-Sacubitril) is the isomer of Sacubitril which is a neprilysin inhibitor.
T25316 Dexecadotril Retorphan
Dexecadotril is a powerful and selective neprilysin inhibitor. It behaves as a prodrug of the enantiomer of thiorphan.
T13125 TD-0212 Others
TD-0212 is an orally active dual pharmacology antagonist of angiotensin II type 1 receptor (AT1) and inhibitor of neprilysin (NEP)(pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP).
T4574L Sacubitril sodium AHU377,AHU-377,LCZ696,AHU 377
Sacubitril is an angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases.
T13125L TD-0212 TFA Others
TD-0212 TFA is an orally active dual pharmacology antagonist of angiotensin II type 1 receptor (AT1) and inhibitor of neprilysin (NEP)(pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP).
T28005 MDL-100240
MDL-100240 is a dual inhibitor of angiotensin-converting enzyme (ACE) and neprilysin with a balanced activity. MDL 100240 shows an impressive effectiveness both in preventing and in regressing hypertension-induced vascul...
T19112 2R,4S-Sacubitril Sacubitril Enantiomer,ahu377 isomer 2 Others
2R,4S-Sacubitril (Sacubitril Enantiomer) is the impurity of Sacubitril which is a neprilysin inhibitor.
T71118 NEP-28
NEP-28 is an AR agonist. NEP28 is a new SARM exhibiting high selectivity for androgen receptor. NEP28 showed tissue-selective effect equivalent to or higher than existing SARMs. In addition, the administration of NEP28 i...
T71145 Racecadotril-d5
Racecadotril-d5 is intended for use as an internal standard for the quantification of racecadotril by GC- or LC-MS. Racecadotril is a prodrug form of the neprilysin (NEP) inhibitor thiorphan. In vivo, racecadotril reduce...
TargetMol