11
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T16741 | Rheb inhibitor NR1 | mTOR | |
Rheb inhibitor NR1 is a Rheb inhibitor and selective mTORC1 inhibitor.Rheb inhibitor NR1 inhibits the phosphorylation of T389pS6K1 and promotes the phosphorylation of S473pAKT. | |||
T22542 | 1-Aminocyclobutanecarboxylic acid | ACBC | NMDAR , iGluR |
1-Aminocyclobutanecarboxylic acid (ACBC) is a NMDA receptor partial agonist. 1-Aminocyclobutanecarboxylic acid act at the glycine site, NR1[1]. | |||
T12251 | NR1H4 activator 1 | Others | |
NR1H4 activator 1 is a potent and selective agonist of Famesoid X Receptor (FXR). | |||
T30554 | BNR10S | bNR 10S,bNR-10S | |
bNR10S is a solvatochromic nile red probe with FRET quencher reveal lipid order heterogeneity in living and apoptotic cells. | |||
T79207 | SUCNR1-IN-1 | ||
SUCNR1-IN-1 (Compound 20) serves as a potent SUCNR1 inhibitor, exhibiting an IC50 of 88 nM against hSUCNR1. It is utilized in the study of rheumatoid arthritis, liver fibrosis, and obesity [1]. | |||
T36474 | TunR1 | ||
TunR1 is an antibiotic and derivative of tunicamycin .1It is active againstB. subtilis(MIC = 0.3 μg/ml) and increases the efficacy of the β-lactam antibiotics oxacillin , methicillin , and penicillin G againstB. subtilis... | |||
T81075 | SUCNR1-IN-2 | ||
SUCNR1-IN-2 (Statement 35) serves as an inhibitor of both succinate and succinate receptor 1, utilized in research pertaining to neurodegenerative disorders, including neuroinflammation [1]. | |||
T8450 | TCN 213 | TCN213 | NMDAR |
TCN 213 is an antagonist of NMDA receptor that has a selective for NR1/NR2A over NR1/NR2B | |||
T2S1008 | Oxysophoridine | Sophoridine N-oxide | Apoptosis , Antioxidant |
Oxysophoridine (Sophoridine N-oxide) has a protective effect on focal cerebral ischemic injury through antioxidant and anti-apoptotic mechanisms; it may be a potential neuroprotective agent for cerebral ischemia injury, ... | |||
T37671 | CAY10608 | CAY10608 | |
N-Methyl-D-aspartate (NMDA) receptors are Ca2+ permeable ligand-gated channels of the central nervous system that are activated after binding of the co-agonists glutamate and glycine. CAY10608 is a propanolamine that pot... | |||
T37215 | 5α,6β-Dihydroxycholestanol | ||
5α,6β-Dihydroxycholestanol is an oxysterol metabolite of cholesterol formed from conversion of cholesterol epoxides by 5,6-epoxysterol hydrolase. It inhibits NMDA-mediated calcium influx in HEK293 cells expressing NR1/NR... |