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Search Results for " nr1 "

11

Compounds

Cat No. Product Name Synonyms Targets
T16741 Rheb inhibitor NR1 mTOR
Rheb inhibitor NR1 is a Rheb inhibitor and selective mTORC1 inhibitor.Rheb inhibitor NR1 inhibits the phosphorylation of T389pS6K1 and promotes the phosphorylation of S473pAKT.
T22542 1-Aminocyclobutanecarboxylic acid ACBC NMDAR , iGluR
1-Aminocyclobutanecarboxylic acid (ACBC) is a NMDA receptor partial agonist. 1-Aminocyclobutanecarboxylic acid act at the glycine site, NR1[1].
T12251 NR1H4 activator 1 Others
NR1H4 activator 1 is a potent and selective agonist of Famesoid X Receptor (FXR).
T30554 BNR10S bNR 10S,bNR-10S
bNR10S is a solvatochromic nile red probe with FRET quencher reveal lipid order heterogeneity in living and apoptotic cells.
T79207 SUCNR1-IN-1
SUCNR1-IN-1 (Compound 20) serves as a potent SUCNR1 inhibitor, exhibiting an IC50 of 88 nM against hSUCNR1. It is utilized in the study of rheumatoid arthritis, liver fibrosis, and obesity [1].
T36474 TunR1
TunR1 is an antibiotic and derivative of tunicamycin .1It is active againstB. subtilis(MIC = 0.3 μg/ml) and increases the efficacy of the β-lactam antibiotics oxacillin , methicillin , and penicillin G againstB. subtilis...
T81075 SUCNR1-IN-2
SUCNR1-IN-2 (Statement 35) serves as an inhibitor of both succinate and succinate receptor 1, utilized in research pertaining to neurodegenerative disorders, including neuroinflammation [1].
T8450 TCN 213 TCN213 NMDAR
TCN 213 is an antagonist of NMDA receptor that has a selective for NR1/NR2A over NR1/NR2B
T2S1008 Oxysophoridine Sophoridine N-oxide Apoptosis , Antioxidant
Oxysophoridine (Sophoridine N-oxide) has a protective effect on focal cerebral ischemic injury through antioxidant and anti-apoptotic mechanisms; it may be a potential neuroprotective agent for cerebral ischemia injury, ...
T37671 CAY10608 CAY10608
N-Methyl-D-aspartate (NMDA) receptors are Ca2+ permeable ligand-gated channels of the central nervous system that are activated after binding of the co-agonists glutamate and glycine. CAY10608 is a propanolamine that pot...
T37215 5α,6β-Dihydroxycholestanol
5α,6β-Dihydroxycholestanol is an oxysterol metabolite of cholesterol formed from conversion of cholesterol epoxides by 5,6-epoxysterol hydrolase. It inhibits NMDA-mediated calcium influx in HEK293 cells expressing NR1/NR...
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