Search Result

Search Results for " mrc "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T64320	ML251		Glucokinase , Parasite
	ML251 is a potent novel nanomolar inhibitor of T. brucei and T. cruzi phosphofructokinase[1]. ML251 inhibits T. brucei PFK (IC50=0.37 μM) and T. cruzi PFK (IC50=0.13 μM). ML251 can be used for the research of parasite[1]...		Glucokinase , Parasite
T20038	2-Fluoroadenine	NSC-27364,NSC 27364,NSC27364	DNA/RNA Synthesis
	2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.		DNA/RNA Synthesis
T16079	Mirodenafil	SK3530	PDE
	Mirodenafil is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.		PDE
TQ0126	Mirodenafil dihydrochloride	SK-3530 dihydrochloride	PDE
	Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.		PDE
T6881L	LTX315 acetate	KKWWKKW-Dip-K-NH2 acetate,Oncopore acetate,Ruxotemitide acetate,LTX315 acetate(1345407-05-7, Free base)	Others
	LTX315 acetate (Oncopore acetate) is an oncolytic peptide with potent anticancer activity, with IC50 values of 34.3 µM for MRC-5, 8.3 µM for A20, and 11 µM for AT84, respectively.		Others
T6881	LTX-315	LTX315,Oncopore,K-K-W-W-K-K-W-Dip-K-NH2	BCL
	LTX-315 (Oncopore), the oncolytic peptide, inhibits cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization.		BCL
T61796	MtTMPK-IN-1
	MtTMPK-IN-1 (compound 3) is a highly effective inhibitor of Mycobacterium tuberculosis thymidylate kinase (Mt TMPK), exhibiting an IC50 value of 2.5 μM. It displays moderate to weak activity against Mtb H37Rv while demon...
T79380	Galectin-3/galectin-8-IN-1		Galectin
	Galectin-3/galectin-8-IN-1 (Compound 53) serves as a dual inhibitor of the Galectin-3 and galectin-8 C-terminal domains, exhibiting dissociation constants (Kd) of 4.12 μM for Galectin-3 and 6.04 μM for galectin-8. It eff...		Galectin
T62897	MtTMPK-IN-3
	MtTMPK-IN-3 (compound 25) is a potent inhibitor of Mycobacterium tuberculosis thymidylate kinase (MtTMPK) with an IC50 value of 0.12 μM. It also demonstrates inhibitory activity against Mtb H37Rv with a MIC of 12.5 μM an...
T79568	NPD-2975		Parasite
	NPD-2975 (compound 30) is an orally active antitrypanosomal agent effective against Human African Trypanosomiasis (HAT), demonstrating acceptable metabolic stability and low toxicity potential in human MRC-5 lung fibrobl...		Parasite
T79381	Galectin-3/galectin-8-IN-2		Galectin
	Galectin-3/galectin-8-IN-2 (Compound 57) is a dual inhibitor targeting the C-terminal domains of Galectin-3 and galectin-8, exhibiting dissociation constants (Kd) of 12.8 μM and 2.06 μM, respectively. It effectively inhi...		Galectin
T62305	MtTMPK-IN-2
	MtTMPK-IN-2 (compound 15), a potent inhibitor of Mycobacterium tuberculosis thymidylate kinase (Mt TMPK), demonstrates an IC50 value of 1.1 μM. This compound effectively inhibits Mtb H37Rv with a minimum inhibitory conce...
T83854	BRC4wt TFA
	BRC4wt, an acetylated peptide originating from the BRC4 repeat within human BRCA2 (1521-1536), acts as an inhibitor of the BRCA2 and RAD51 protein-protein interaction. When linked to the cationic cell-penetrating peptide...
T83865	HP661
	HP661, a selective inhibitor of mitochondrial complex I (NADH dehydrogenase), impedes complex I activity by 77.6% at 1 µM, demonstrating lesser inhibition towards complex III (28.1%) and no inhibitory effects on complexe...

Compounds

ML251

T64320

Synonym:

Target: Glucokinase, Parasite

2-Fluoroadenine

T20038

Synonym: NSC-27364,NSC 27364,NSC27364

Target: DNA/RNA Synthesis

Mirodenafil dihydrochloride

TQ0126

Synonym: SK-3530 dihydrochloride

Target: PDE

LTX315 acetate

T6881L

Synonym: KKWWKKW-Dip-K-NH2 acetate,Oncopore acetate,Ruxotemitide acetate,LTX315 acetate(1345407-05-7, Free base)

Target: Others

LTX-315

T6881

Synonym: LTX315,Oncopore,K-K-W-W-K-K-W-Dip-K-NH2

Galectin-3/galectin-8-IN-1

Galectin-3/galectin-8-IN-2

Cat No.	Product Name	Synonyms	Targets
T36954	Nemorosone
	Nemorosone is a polycyclic polyprenylated acylphloroglucinol (PPAP) originally isolated from C. rosea that has antiproliferative properties.1 Nemorosone inhibits growth of NB69, Kelly, SK-N-AS, and LAN-1 neuroblastoma ce...

Natural Products

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-05446	CD200 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	CD200 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.2 kDa and the accession number is A0A2R9ADU6.
TMPY-05638	CD200 Protein, Human, Recombinant (hFc & Avi)	Human	HEK293 Cells
	CD200 Protein, Human, Recombinant (hFc & Avi) is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 51 kDa and the accession number is P41217-2.
TMPY-01071	CD200 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CD200 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is P41217-2.
TMPY-06791	CD200 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	CD200 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 25.71 kDa and the accession number is NP_005935.4.
TMPK-00733	CD200 Protein, Mouse, Recombinant (aa 31-232, His)	Mouse	HEK293 Cells
	CD200 and its receptors are highly expressed in the lung, on epithelial cells and leukocytes, and emerging evidence links dysregulation of the CD200 pathway with asthma. Moreover, pharmacological modulation of CD200 rece...
TMPK-00476	CD200 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	CD200 and its receptors are highly expressed in the lung, on epithelial cells and leukocytes, and emerging evidence links dysregulation of the CD200 pathway with asthma. Moreover, pharmacological modulation of CD200 rece...
TMPH-01632	MRC1 Protein, Human, Recombinant (His)	Human	E. coli
	Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains.; (Microbial infection) Acts as phagocytic receptor for bacteria, fungi and other pathogens.; (Microbia...
TMPK-01225	MRC2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	MRC2 (Mannose Receptor C Type 2) is a constitutively recycling endocytic receptor belonging to the mannose receptor family, which has been found to be closely involved with cancer metastasis. MRC2 expresses an extracellu...
TMPK-00574	MRC2 Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	MRC2 (Mannose Receptor C Type 2) is a constitutively recycling endocytic receptor belonging to the mannose receptor family, which has been found to be closely involved with cancer metastasis. MRC2 expresses an extracellu...