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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3256 | MMAF | MonoMethyl auristatin F | Others , Microtubule Associated |
MMAF (MonoMethyl auristatin F), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin. | |||
T12081 | MMAF-OMe | Monomethyl auristatin F methyl ester | |
MMAF-OMe (Monomethyl auristatin F methyl ester) is an antitubulin agent which inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji ... | |||
T39897 | DBCO-PEG4-MMAF | DBCO-PEG4-MMAF | |
DBCO-PEG4-MMAF is an antibody-drug conjugate (ADC) component that exhibits potent antitumor activity. It combines the tubulin polymerization inhibitor MMAF with a cleavable linker, DBCO-PEG4, to target cancer cells effec... | |||
T38830 | Modified MMAF-C5-COOH | Modified MMAF-C5-COOH | |
Modified MMAF-C5-COOH is a drug-linker conjugate for ADC. | |||
T39238 | DBM-MMAF | ||
DBM-MMAF is a drug-linker conjugate composed of a potent antitubulin agent MMAF and a linker DBM to make antibody drug conjugate (ADC). | |||
T39748 | DBCO-PEG4-Val-Cit-PAB-MMAF | DBCO-PEG4-Val-Cit-PAB-MMAF | |
DBCO-PEG4-Val-Cit-PAB-MMAF is a chemical compound that comprises a cleavable 4 unit polyethylene glycol antibody-drug conjugate (ADC) linker known as DBCO-PEG4-Val-Cit-PAB, and a highly effective inhibitor of tubulin pol... | |||
T16121 | MMAF Hydrochloride | Monomethylauristatin F Hydrochloride | Others |
MMAF Hydrochloride is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A. MMAF Hydrochloride is an effective tubulin polymerization inhibitor and is used ... | |||
T10949 | D8-MMAF | Monomethylauristatin F D8 | Others |
D8-MMAF is a microtubule destroyer, deuterated form of MMAF. | |||
T19269 | D8-MMAF hydrochloride | Others | |
D8-MMAF hydrochloride is a deuterated form of MMAF hydrochloride, which is a microtubule destroyer. | |||
T16122 | MMAF sodium | Monomethylauristatin F sodium | ABC |
MMAF sodium is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A. MMAF sodium is an effective tubulin polymerization inhibitor and is used as an antitumo... | |||
T27975 | MAL-PEG4-MMAF | ||
MAL-PEG4-MMAF is a maleimido functionalized derivative of MMAF (Monomethyl auristatin F) with PEG4 linker. The maleimido functional group can be easily conjugated to protein carriers (such as antibody or enzyme). MAL-PEG... | |||
T18534 | PEG4-aminooxy-MMAF | Others | |
PEG4-aminooxy-MMAF is a drug-linker conjugate designed for antibody-drug conjugates (ADC) that exhibits potent antitumor activity. It incorporates MMAF, a powerful antitubulin agent, connected through a non-cleavable PEG... | |||
T18306 | MC-Alkyl-Hydrazine Modified MMAF | Others | |
MC-Alkyl-Hydrazine Modified MMAF is a potent antitumor drug-linker conjugate for ADC, incorporating Modified MMAF, a tubulin inhibitor, through a noncleavable MC-Alkyl-Hydrazine linkage[1]. | |||
T18326 | MC-Val-Cit-PAB-MMAF | Others | |
MC-Val-Cit-PAB-MMAF is an antibody-drug conjugate (ADC) component that exhibits antitumor properties through the action of the tubulin inhibitor, monomethyl auristatin F (MMAF), which is connected by a cathepsin-cleavabl... | |||
T18251 | MAL-di-EG-Val-Cit-PAB-MMAF | Others | |
MAL-di-EG-Val-Cit-PAB-MMAF refers to a chemical compound that comprises the linker (MAL-di-EG-Val-Cit-PAB) and the potent blocker of tubulin polymerization (MMAF, Monomethyl auristatin F)[1]. | |||
T74177 | Modified MMAF | ||
Modified MMAF, a cytotoxin for antibody-drug conjugates (ADC), facilitates the synthesis of ADCs tailored for targeted cancer research [1]. | |||
T83129 | Amidate-VC-PAB-MMAF | ||
Amidate-VC-PAB-MMAF, a cleavable ADC linker (Amidate-VC-PAB) combined with a potent tubulin polymerization inhibitor (MMAF), is utilized in the synthesis of antibody-drug conjugates (ADCs) to decrease off-target cytotoxi... | |||
T82382 | Fmoc-MMAF-OMe | ||
Fmoc-MMAF-OMe is a tubulin polymerization inhibitor and anticancer agent featuring an Fmoc protecting group. Its active component, MMAF, serves as the cytotoxic (ADC Cytotoxin) element in conventional antibody-drug conju... | |||
T80883 | Val-Cit-PAB-MMAF | ||
Val-Cit-PAB-MMAF is an agent-linker conjugate utilized for antibody-drug conjugates (ADCs), consisting of the peptide linker Val-Cit-PAB and the potent tubulin polymerization inhibitor known as MMAF [1]. | |||
T77894 | Val-Cit-PAB-MMAF sodium | ||
Val-Cit-PAB-MMAF sodium is an agent-linker conjugate used in antibody-drug conjugates (ADCs), consisting of the peptide linker Val-Cit-PAB and the cytotoxic agent monomethyl auristatin F (MMAF), which inhibits tubulin po... |