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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T39849 | Propargite | Parasite | |
Propargite is a pesticide used to kill mites. Propargite induces β-cell necrosis preceded by DNA damage. Propargite induces MIN6 cell death with an IC 50 of 1 μM [1] . | |||
T4423 | LY 303511 hydrochloride | LY303511 hydrochloride | Potassium Channel , TNF , mTOR |
LY 303511 hydrochloride is a potent mTOR inhibitor | |||
T11401 | GKA50 | Others | |
GKA50 stimulates insulin release from mouse islets of Langerhans and MIN6 cells. GKA50 shows significant glucose lowering in high fat fed female rats. GKA50 is a potent glucokinase activator (EC50=33 nM at 5 mM glucose). | |||
T2434 | LY 303511 | Potassium Channel , TNF , mTOR | |
LY303511, an inactive analogue of LY294002, is a mTOR inhibitor and no inhibition for PI3-K. | |||
T83827 | Adenosine-5'-O-(3-thiotriphosphate) sodium | ATPγS,Adenosine 5'-(γ-thio)-triphosphate | |
Adenosine-5'-O-(3-thiotriphosphate) (ATPγS), an agonist of the purinergic P2Y11 receptor, prompts inositol phosphate accumulation in CHO-K1 cells harboring the human or canine P2Y11 receptor with EC50 values of 1.2 and 1... | |||
T14215 | AMG 837 sodium salt | Others | |
AMG 837 sodium salt is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. IC50 value: 13 nM (EC50) [1] Target: GPR40 agoni... | |||
T14216 | AMG 837 | Others | |
AMG 837 is a partial GPR40 agonist with an EC50 value of 13 nM, showcasing 85% of the maximal activity displayed by DHA in standard assay conditions, indicating its high potency and selectivity in vitro. This compound ex... |