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Search Results for " min6 "

7

Compounds

Cat No. Product Name Synonyms Targets
T39849 Propargite Parasite
Propargite is a pesticide used to kill mites. Propargite induces β-cell necrosis preceded by DNA damage. Propargite induces MIN6 cell death with an IC 50 of 1 μM [1] .
T4423 LY 303511 hydrochloride LY303511 hydrochloride Potassium Channel , TNF , mTOR
LY 303511 hydrochloride is a potent mTOR inhibitor
T11401 GKA50 Others
GKA50 stimulates insulin release from mouse islets of Langerhans and MIN6 cells. GKA50 shows significant glucose lowering in high fat fed female rats. GKA50 is a potent glucokinase activator (EC50=33 nM at 5 mM glucose).
T2434 LY 303511 Potassium Channel , TNF , mTOR
LY303511, an inactive analogue of LY294002, is a mTOR inhibitor and no inhibition for PI3-K.
T83827 Adenosine-5'-O-(3-thiotriphosphate) sodium ATPγS,Adenosine 5'-(γ-thio)-triphosphate
Adenosine-5'-O-(3-thiotriphosphate) (ATPγS), an agonist of the purinergic P2Y11 receptor, prompts inositol phosphate accumulation in CHO-K1 cells harboring the human or canine P2Y11 receptor with EC50 values of 1.2 and 1...
T14215 AMG 837 sodium salt Others
AMG 837 sodium salt is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. IC50 value: 13 nM (EC50) [1] Target: GPR40 agoni...
T14216 AMG 837 Others
AMG 837 is a partial GPR40 agonist with an EC50 value of 13 nM, showcasing 85% of the maximal activity displayed by DHA in standard assay conditions, indicating its high potency and selectivity in vitro. This compound ex...
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