Home Tools
Log in
Cart

Search Result

Search Results for " lapatinib "

8

Compounds

Cat No. Product Name Synonyms Targets
T0078 Lapatinib GSK572016,GW572016 EGFR , Ferroptosis , Autophagy
Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity. Lapatinib has antitumor activity and can be used to treat advanced or metastatic breast cancer with HER2 overexpression.
T0078L Lapatinib ditosylate monohydrate Lapatinib ditosylate monohydrate,Lapatinib ditoluenesulfonate monohydrate,Lapatinib tosilate hydrate,Lapatinib tosilate,Tykerb,Tyverb EGFR , Ferroptosis , Autophagy
Lapatinib ditosylate (Lapatinib tosilate) monohydrate is a tyrosine kinase receptor inhibitor used in the therapy of advanced breast cancer and other solid tumors. Lapatinib ditosylate monohydrate therapy is associated w...
T6235 Lapatinib Ditosylate Lapatinib (GW-572016) Ditosylate,GW-572016 ditosylate,Tykerb ditosylate EGFR , Ferroptosis , Autophagy
Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).
T0077 Dantrolene sodium Lapatinib ditosylate monohydrate,Dantrolene sodium salt Others , Calcium Channel
Dantrolene sodium (Lapatinib ditosylate monohydrate) salt is a skeletal muscle relaxant and can interfere with excitation-contraction coupling in the muscle fiber. It is used for the treatment of spasticity and other neu...
T72577 Lapatinib tosylate GW2016 tosylate,GW572016 tosylate,GW572016 tosylate ; GW2016 tosylate
Lapatinib tosylate (GW572016), a robust and orally administered inhibitor specifically targeting the tyrosine kinase domains of ErbB-2 and EGFR, exhibits inhibitory concentration 50 (IC50) values of 10.2 nM and 9.8 nM ag...
T6092 Sapitinib AZD-8931 EGFR
Sapitinib (AZD-8931) , a reversible, ATP competitive inhibitor of EGFR(IC50=4 nM), ErbB2(IC50=3 nM) and ErbB3(IC50=4 nM), is more effective over Gefitinib or Lapatinib against NSCLC cell, 100-fold more specific for the E...
T36244 SJF 1521
Selective EGFR Degrader. Comprises the EGFR inhibitor lapatinib (Cat. No. 6811) joined by a linker to a von Hippel-Lindau (VHL) recruiting ligand. Exhibits selectivity for EGFR, including mutant forms, over HER2. Induces...
T36245 SJF 1528
Potent EGFR Degrader (DC50 values are 39.2 nM for wild-type EGFR in OVCAR8 cells and 736 nM for Exon20Ins mutated EGFR in HeLa cells). Also degrades HER2. Comprises the EGFR inhibitor lapatinib (Cat. No. 6811) joined by ...
TargetMol