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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6593 | ML324 | Histone Demethylase , Others , HSV | |
ML324(IC50=920 nM) is a specific inhibitor of jumonji histone demethylase (JMJD2). | |||
T1816 | (Z)-JIB-04 | NSC 693627,Z-JIB-04 | Others |
(Z)-JIB-04 (NSC 693627) is an isomer of JIB-04. | |||
T1868 | JIB-04 | JIB 04,NSC 693627 | Apoptosis , Histone Demethylase , Histone Methyltransferase |
JIB-04 (NSC 693627) is a pan-selective Jumonji histone demethylase inhibitor. | |||
T16435 | PBIT | Histone Demethylase , Histone Methyltransferase | |
PBIT inhibits JARID1B histone demethylase (IC50 of about 3 μM). PBIT also inhibits JARID1A and JARID1C (IC50s of 6 μM and 4.9 μM, respectively). PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (J... | |||
T38774 | E67-2 | E67-2 | |
E67-2, a derivative of E67, is a low-toxicity, selective inhibitor of the KIAA1718 Jumonji domain. It has an IC 50 value of 3.4 μM. E67-2 specifically inhibits the Jumonji demethylase for histone H3 lysine 9 (H3K9) and h... | |||
T75175 | JHDM-IN-1 | ||
JHDM-IN-1 (Compound 1), a Jumonji C domain-containing HDMs (JHDM) inhibitor, exhibits IC50s of 3.4 μM against JMJD2C, 4.3 μM against JMJD2A, 5.9 μM against JMJD2E, 10 μM against PHF8, and 43 μM against JMJD3, showcasing ... | |||
T68436 | Prohexadione | ||
Prohexadione is a plant growth regulator. It inhibits the gibberellin plant hormone biosynthesis enzyme 3β-hydroxylase when used at concentrations of 0.1, 1, and 10 mM. It reduces the shoot length of peanut plants when a... | |||
T79713 | JMJD3/HDAC-IN-1 | HDAC | |
Compound A5b, also known as JMJD3/HDAC-IN-1, is a dual inhibitor that targets both JMJD3 (Jumonji domain-containing protein demethylase 3) and HADC1 (histone deacetylase, IC50 = 16 nM). It induces hypermethylation of his... | |||
T7057 | Methylstat | Histone Demethylase , Others | |
Methylstat is a methyl ester prodrug of a Jumonji C domain-containing histone demethylase (JMJD) inhibitor that has favorable cell permeability. The free acid of methylstat inhibits JMJD2A, JMJD2C, JMJD2E, PHF8, and JMJD... |