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Search Results for " jumonji "

9

Compounds

Cat No. Product Name Synonyms Targets
T6593 ML324 Histone Demethylase , Others , HSV
ML324(IC50=920 nM) is a specific inhibitor of jumonji histone demethylase (JMJD2).
T1816 (Z)-JIB-04 NSC 693627,Z-JIB-04 Others
(Z)-JIB-04 (NSC 693627) is an isomer of JIB-04.
T1868 JIB-04 JIB 04,NSC 693627 Apoptosis , Histone Demethylase , Histone Methyltransferase
JIB-04 (NSC 693627) is a pan-selective Jumonji histone demethylase inhibitor.
T16435 PBIT Histone Demethylase , Histone Methyltransferase
PBIT inhibits JARID1B histone demethylase (IC50 of about 3 μM). PBIT also inhibits JARID1A and JARID1C (IC50s of 6 μM and 4.9 μM, respectively). PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (J...
T38774 E67-2 E67-2
E67-2, a derivative of E67, is a low-toxicity, selective inhibitor of the KIAA1718 Jumonji domain. It has an IC 50 value of 3.4 μM. E67-2 specifically inhibits the Jumonji demethylase for histone H3 lysine 9 (H3K9) and h...
T75175 JHDM-IN-1
JHDM-IN-1 (Compound 1), a Jumonji C domain-containing HDMs (JHDM) inhibitor, exhibits IC50s of 3.4 μM against JMJD2C, 4.3 μM against JMJD2A, 5.9 μM against JMJD2E, 10 μM against PHF8, and 43 μM against JMJD3, showcasing ...
T68436 Prohexadione
Prohexadione is a plant growth regulator. It inhibits the gibberellin plant hormone biosynthesis enzyme 3β-hydroxylase when used at concentrations of 0.1, 1, and 10 mM. It reduces the shoot length of peanut plants when a...
T79713 JMJD3/HDAC-IN-1 HDAC
Compound A5b, also known as JMJD3/HDAC-IN-1, is a dual inhibitor that targets both JMJD3 (Jumonji domain-containing protein demethylase 3) and HADC1 (histone deacetylase, IC50 = 16 nM). It induces hypermethylation of his...
T7057 Methylstat Histone Demethylase , Others
Methylstat is a methyl ester prodrug of a Jumonji C domain-containing histone demethylase (JMJD) inhibitor that has favorable cell permeability. The free acid of methylstat inhibits JMJD2A, JMJD2C, JMJD2E, PHF8, and JMJD...
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