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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2502 | INH1 | IBT13131 | Apoptosis , Microtubule Associated |
INH1 (IBT13131) is a cell-permeable Hec1 inhibitor that specifically disrupts the Hec1/Nek2 interaction. | |||
T74906 | ODN 20844 | ||
ODN 20844, a guanine-modified inhibitory oligonucleotide (INH-ODN), serves as an inhibitor for TLR7 and TLR9 (Toll-like receptors), originating from its parent compound INH-ODN 2088. It specifically impedes immune cell r... | |||
T79559 | Mtb-IN-4 | ||
Mtb-IN-4 (compound 17h) is a non-toxic isoxazole that exhibits anti-Mycobacterium tuberculosis (Mtb) activity, with an IC50 value of 0.70 μM. It impedes Mtb respiration and biofilm formation within macrophages and augmen... | |||
T79561 | Mtb-IN-5 | ||
Mtb-IN-5 (compound (-)17j) is an isoxazole exhibiting anti-Mycobacterium tuberculosis (Mtb) activity. It impedes Mtb respiration and biofilm formation within macrophages and augments the efficacy of the antibiotic isonia... | |||
T35883 | RNF5 inhibitor inh-02 | RNF5 inhibitor inh-02 | |
RNF5 inhibitor inh-02, a potent E3 ubiquitin ligase RNF5/RMA1 inhibitor, demonstrates significant efficacy in rescuing F508del-CFTR with an EC50 of 2.2 uM in bronchial epithelial cells homozygous for the F508del mutation... | |||
T74912 | ODN 24991 | ||
ODN 24991, a guanine-modified inhibitory oligonucleotide (INH-ODN) derivative of INH-ODN 2088, inhibits Toll-like receptors (TLR) 3, TLR7, and TLR9, thereby attenuating TLR3-, TLR7-, and TLR9-mediated immune responses. T... | |||
T74872 | ODN 105870 | ||
ODN 105870, a G-modified inhibitory oligonucleotide (INH-ODN), selectively inhibits TLR7 and is utilized in the research of inflammatory immune responses [1]. | |||
T38073 | Thiocarlide | Isoxyl | |
Thiocarlide (isoxyl) is a thiourea derivative that was used in the 1960s to successfully treat tuberculosis (TB). It has considerable antimycobacterial activity in vitro and is effective against multi-drug resistant stra... | |||
T74873 | ODN 105871 | ||
ODN 105871, a G-modified inhibitory oligonucleotide (INH-ODN), acts as a selective inhibitor of Toll-like receptor 7 (TLR7). It is utilized in the study of inflammatory immune responses [1]. | |||
T74910 | ODN 24888 | ||
ODN 24888, a guanine-modified inhibitory oligonucleotide (INH-ODN), effectively inhibits TLR7/TLR9-mediated signaling, reducing IFN-α levels and NF-κB activation, and suppressing IL-6 release. This compound plays a role ... | |||
T74907 | ODN 21595 | ||
ODN 21595, a guanine-modified inhibitor targeting TLR7 and TLR9, effectively inhibits the release of IFN-α and IL-6 without exhibiting cytotoxicity. It also reduces the expression of CD86 and HLA-DR, showcasing potential... | |||
T37880 | OPC-167832 | ||
OPC-167832 is a potent and orally active dprE1 Inhibitor with an IC50 of 0.258 μM. OPC-167832 has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis[1]. OPC-16... |