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Search Results for " inh-1 "

12

Compounds

Cat No. Product Name Synonyms Targets
T2502 INH1 IBT13131 Apoptosis , Microtubule Associated
INH1 (IBT13131) is a cell-permeable Hec1 inhibitor that specifically disrupts the Hec1/Nek2 interaction.
T74906 ODN 20844
ODN 20844, a guanine-modified inhibitory oligonucleotide (INH-ODN), serves as an inhibitor for TLR7 and TLR9 (Toll-like receptors), originating from its parent compound INH-ODN 2088. It specifically impedes immune cell r...
T79559 Mtb-IN-4
Mtb-IN-4 (compound 17h) is a non-toxic isoxazole that exhibits anti-Mycobacterium tuberculosis (Mtb) activity, with an IC50 value of 0.70 μM. It impedes Mtb respiration and biofilm formation within macrophages and augmen...
T79561 Mtb-IN-5
Mtb-IN-5 (compound (-)17j) is an isoxazole exhibiting anti-Mycobacterium tuberculosis (Mtb) activity. It impedes Mtb respiration and biofilm formation within macrophages and augments the efficacy of the antibiotic isonia...
T35883 RNF5 inhibitor inh-02 RNF5 inhibitor inh-02
RNF5 inhibitor inh-02, a potent E3 ubiquitin ligase RNF5/RMA1 inhibitor, demonstrates significant efficacy in rescuing F508del-CFTR with an EC50 of 2.2 uM in bronchial epithelial cells homozygous for the F508del mutation...
T74912 ODN 24991
ODN 24991, a guanine-modified inhibitory oligonucleotide (INH-ODN) derivative of INH-ODN 2088, inhibits Toll-like receptors (TLR) 3, TLR7, and TLR9, thereby attenuating TLR3-, TLR7-, and TLR9-mediated immune responses. T...
T74872 ODN 105870
ODN 105870, a G-modified inhibitory oligonucleotide (INH-ODN), selectively inhibits TLR7 and is utilized in the research of inflammatory immune responses [1].
T38073 Thiocarlide Isoxyl
Thiocarlide (isoxyl) is a thiourea derivative that was used in the 1960s to successfully treat tuberculosis (TB). It has considerable antimycobacterial activity in vitro and is effective against multi-drug resistant stra...
T74873 ODN 105871
ODN 105871, a G-modified inhibitory oligonucleotide (INH-ODN), acts as a selective inhibitor of Toll-like receptor 7 (TLR7). It is utilized in the study of inflammatory immune responses [1].
T74910 ODN 24888
ODN 24888, a guanine-modified inhibitory oligonucleotide (INH-ODN), effectively inhibits TLR7/TLR9-mediated signaling, reducing IFN-α levels and NF-κB activation, and suppressing IL-6 release. This compound plays a role ...
T74907 ODN 21595
ODN 21595, a guanine-modified inhibitor targeting TLR7 and TLR9, effectively inhibits the release of IFN-α and IL-6 without exhibiting cytotoxicity. It also reduces the expression of CD86 and HLA-DR, showcasing potential...
T37880 OPC-167832
OPC-167832 is a potent and orally active dprE1 Inhibitor with an IC50 of 0.258 μM. OPC-167832 has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis[1]. OPC-16...
TargetMol