il-35 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T70484	AD-35
	AD-35 is a neuroprotectant for treating Alzheimer’s diseases by significantly inhibiting the production and release of proinflammatory cytokines TNF-α and IL-1β.
T78688	HPK1-IN-35
	HPK1-IN-35 is a potent, selective inhibitor of HPK1, demonstrating an IC50 value of 3.5 nM. This compound reduces p-SLP76 expression and facilitates the secretion of IL-2 [1].
T37590	ML 3403
	p38 MAPK inhibitor (IC50 = 0.38 μM). Inhibits the release of IL-1β and TNF-α in a peripheral blood mononuclear cell (PBMC) assay (IC50 values are 0.039 and 0.16 μM respectively). Laufer et al (2003) Novel substituted pyr...
T38106	JC-171
	JC-171, a selective inhibitor of the NLRP3 inflammasome, effectively inhibits LPS/ATP-induced interleukin-1β (IL-1β) release from J774A.1 macrophages with an IC50 of 8.45 μM[1].

Compounds

AD-35

T70484

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04793	IL-35 Protein, Human, Recombinant (Flag & His)	Human	HEK293 Cells
	IL-35 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 48.3 kDa and the accession number is P29459-1.
TMPY-03879	IL-35 Protein, Human, Recombinant	Human	HEK293 Cells
	IL-35 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 102 kDa and the accession number is P29459-1.
TMPY-06105	IL-35 Protein, Human, Recombinant (Fc-Flag & Fc-His)	Human	HEK293 Cells
	IL-35 Protein, Human, Recombinant (Fc-Flag & Fc-His) is expressed in HEK293 mammalian cells with Fc-Flag, Fc-His tag. The predicted molecular weight is 102.1 kDa and the accession number is Q14213.
TMPY-04863	IL-12 Protein, Human, Recombinant	Human	HEK293 Cells
	IL-12 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 57.2 kDa and the accession number is P29459-1&NP_002178.2.
TMPY-00838	IL-12A Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IL-12A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.3 kDa and the accession number is P29459.
TMPY-01409	IL-12A Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-12A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is P29459.
TMPY-05458	IL-12 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	IL-12 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60.13 kDa and the accession number is P29459.2&NP_002178.2.
TMPY-02109	IL-12 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-12 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60.13 kDa and the accession number is P29459-1&NP_002178.2.
TMPY-01371	IL-17RA Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-17RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35 kDa and the accession number is Q96F46-1.
TMPJ-00594	IL-13 Protein, Human, Recombinant (Avi & His), Biotinylated	Human	HEK293 Cells
	IL-13 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 22-35 KDa and the accession number is AAK53823.
TMPY-00755	IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99, hFc)	Human	HEK293 Cells
	IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35 kDa and the accession number is A0A024RDA5.
TMPJ-00216	IL-12B Protein, Human, Recombinant	Human	HEK293 Cells
	Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a cytokine that acts on T and natural killer cells, a...