hsf1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8858	DTHIB		HSP
	DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation.		HSP
TN6729	Azadiradione	AZD	Others
	Azadiradione (AZD) (AZD) from the methanolic extract of seeds of Azadirachta indica		Others
T5826	Eupalinolide A		HSP
	Eupalinolide B is a natural product ,and demonstrates potent cytotoxicity against A-549, BGC-823, SMMC-7721, and HL-60 tumour cell lines.		HSP
T4125	HSF1A		HSP
	HSF1A is a cell-permeable activator of HSF1 that protects mammalian cells against stress-induced apoptosis.		HSP
T9804	NPX800	CCT361814	HSP
	NPX800 is an inhibitor of heat shock factor 1 (HSF1) and can be used in studies about the treatment of cancer.		HSP
TQ0280	Feretoside		HSP
	Feretoside is a natural product extracted from the barks of E. ulmoides. Feretoside shows inducible activity on the heat shock factor 1 (HSF1).		HSP
T21852	AEG 3482		Apoptosis
	AEG 3482 is a potent antiapoptotic compound. AEG 3482 inhibits Jun kinase (JNK) activity through induced expression of heat shock protein 70 (HSP70). AEG 3482 directly binds HSP90, thereby facilitating HSF1-dependent exp...		Apoptosis
T3652	KRIBB11		Apoptosis , HSP
	KRIBB11 is an inhibitor of Heat shock factor (HSF) inhibitor.		Apoptosis , HSP
TQ0131	Rocaglamide	Rocaglamide A,Roc-A	HSP , NF-κB , PERK
	Rocaglamide (Roc-A), isolated from the genus Aglaia, can be used to treat coughs, injuries, asthma, and inflammatory skin diseases. It is a potent inhibitor of NF-κB activation in T-cells.		HSP , NF-κB , PERK
T14905	CCT251236		HSP
	CCT251236 is an orally available Pirin ligand obtained from a heat shock transcription factor 1 (hsf1) phenotypic screen. It inhibits HSF1-mediated HSP72 induction (IC50: 19 nM).		HSP
T68755	NZ-28
	NZ28, also known as NSC134754, is potent HSF1 inhibitor, which induced inhibition of HSF1, SP1 and NF-κB triggers the loss of the natural killer cell-activating ligands MICA/B on human tumor cells. Heat-shock transcript...
T62775	CCT245232
	CCT245232 is a potent inhibitor of heat-stimulated factor 1 (HSF1). CCT245232 has the potential to be used in studies of proliferative diseases such as cancer.
T38045	Cholesterol β-D-Glucoside
	Cholesterol β-D-glucoside is a derivative of cholesterol that contains β-D-glucose . It is formed from cholesterol and glucosylceramide by β-glucosidase 1. It activates heat shock transcription factor 1 (Hsf1) in respons...
T71552	ASC-JM-17
	ASC-JM-17 is an activator of both Nrf1 and Nrf2 proteins. ASC-JM17 acts on Nrf1, Nrf2 and Hsf1 to increase the expression of proteasome subunits, antioxidant enzymes and molecular chaperones. ASC-JM17 ameliorates toxicit...
TN3572	Calyxin H		HSP
	Calyxin H at 1uM can increase the expression of heat shock factor 1 (HSF1), it has a possible application as a heat shock protein (HSP) inducer.		HSP
T68582	Tonantzitlolone
	Tonantzitlolone is a natural agonist of tprc1/4/5 channels, also acting as a dual pkcα and pkcθ activator, inducing an insulin resistant phenotype by inhibiting irs1 and the pi3k/akt pathway, activating the heat shock ...