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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4125 | HSF1A | HSP | |
HSF1A is a cell-permeable activator of HSF1 that protects mammalian cells against stress-induced apoptosis. | |||
T3652 | KRIBB11 | Apoptosis , HSP | |
KRIBB11 is an inhibitor of Heat shock factor (HSF) inhibitor. | |||
T3594 | ML346 | HSP | |
ML346 is a novel activator of Hsp70. | |||
T6029 | ONX-0914 | ONX0914,PR-957,ONX 0914 | Proteasome , HIV Protease , Antibacterial |
ONX-0914 (PR-957) is an effective and specific immunoproteasome inhibitor, which has minimal cross-reactivity for the constitutive proteasome. | |||
T30111 | AR 12465 | AR-12465 | |
AR 12465 is a trapidil derivative which may affect LDL receptor mediated uptake and degradation of 125 I-LDL by human skin fibroblasts (HSF) and human hepatic cells (HEP G2). | |||
T79397 | Neutrophil elastase inhibitor 4 | ||
Neutrophil elastase inhibitor 4 (compound 4f) is a competitive inhibitor of human neutrophil elastase (HNE) with IC50 of 42.30 nM and Ki of 8.04 nM. It prompts apoptosis in T47D cells and inhibits the proliferation of T4... | |||
T73986 | ONX-0914 TFA | ||
ONX-0914 (PR-957) TFA is a selective, noncompetitive, irreversible inhibitor targeting the chymotrypsin-like subunit (LMP7) of the immunoproteasome, effectively blocking cytokine production and mitigating the progression... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T21893 | Luffariellolide | ||
Luffariellolide is an inhibitor of human synovial fluid phospholipase A2 ( HSF-PLA2 ) (IC 50 =5 μM). PMA-induced ear edema was effectively inhibited by luffariellolide (ED 50 =50 μg/ear) [1]. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00863 | IL-6 Protein, Human, Recombinant | Human | E. coli |
IL-6 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 20.95 kDa and the accession number is P05231. | |||
TMPJ-01080 | HSF2 Protein, Human, Recombinant (His) | Human | E. coli |
Heat Shock Factor Protein 2 (HSF2) belongs to the HSF family of transcription factors that bind specifically to the heat-shock promoter element and activate transcription. In higher eukaryotes, HSF is unable to bind to t... | |||
TMPK-00101 | IL-6 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression.Interleukin 6 has been shown to interact with interleukin-6 recep... | |||
TMPY-02072 | HSF1 Protein, Human, Recombinant (His) | Human | E. coli |
Heat shock factor protein 1, also known as heat shock transcription factor 1, HSF1, and HSTF1, is a cytoplasm and nucleus protein that belongs to the HSF family. HSF1 is the major transcription factor of HSPs (heat shock... |