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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T32104 | Hras-1Y i-motif Probe-1 | ||
Hras-1Y i-motif Probe-1 is a probe of the hras-1Y i-motif which selectively and directly interacts with it. | |||
T8970 | ML162 | Ferroptosis , GPX , Glutathione Peroxidase | |
ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively) | |||
T81263 | RMC-7977 | Ras | |
RMC-7977 is a reversible triple complex RAS inhibitor that exhibits broad-spectrum activity against mutant and wild-type (WT) variants of KRAS, NRAS, and HRAS. The compound is capable of triggering tumor regression and h... | |||
T28733 | SCH-53870 | ||
SCH-53870 inhibits p21-hRas nucleotide exchange in vitro. | |||
T64000 | MRTX-EX185 | ||
MRTX-EX185 is an effective inhibitor of GDP-loaded KRAS and KRAS (G12D) with an IC50=90 nM for KRAS (G12D). MRTX-EX185 is also capable of binding GDP-loaded HRAS. | |||
T36641 | RAS inhibitor Abd-7 | ||
RAS inhibitor Abd-7 is a powerful compound (Kd=51 nM) that binds to RAS and inhibits the protein-protein interaction (PPI) between RAS and its effectors. By interacting with RAS within cells, RAS inhibitor Abd-7 hinders ... |