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Search Results for " hras "

6

Compounds

Cat No. Product Name Synonyms Targets
T32104 Hras-1Y i-motif Probe-1
Hras-1Y i-motif Probe-1 is a probe of the hras-1Y i-motif which selectively and directly interacts with it.
T8970 ML162 Ferroptosis , GPX , Glutathione Peroxidase
ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively)
T81263 RMC-7977 Ras
RMC-7977 is a reversible triple complex RAS inhibitor that exhibits broad-spectrum activity against mutant and wild-type (WT) variants of KRAS, NRAS, and HRAS. The compound is capable of triggering tumor regression and h...
T28733 SCH-53870
SCH-53870 inhibits p21-hRas nucleotide exchange in vitro.
T64000 MRTX-EX185
MRTX-EX185 is an effective inhibitor of GDP-loaded KRAS and KRAS (G12D) with an IC50=90 nM for KRAS (G12D). MRTX-EX185 is also capable of binding GDP-loaded HRAS.
T36641 RAS inhibitor Abd-7
RAS inhibitor Abd-7 is a powerful compound (Kd=51 nM) that binds to RAS and inhibits the protein-protein interaction (PPI) between RAS and its effectors. By interacting with RAS within cells, RAS inhibitor Abd-7 hinders ...
TargetMol