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Search Result

Search Results for " hdac-in-30 "

8

Compounds

Cat No. Product Name Synonyms Targets
T62006 HDAC-IN-30
HDAC-IN-30 is a multi-target HDAC inhibitor. HDAC-IN-30 inhibits HDAC1 (IC50 =13.4 nM), HDAC2 (IC50 =28.0 nM), HDAC3 (IC50 =9.18 nM), HDAC6 (IC50 =42.7 nM), HDAC8 (IC50 =131 nM). HDAC-IN-30 shows potent antitumor efficac...
T60082 HDAC-IN-40 HDAC
HDAC-IN-40 is a potent alkoxyamide-based HDAC inhibitor with Ki of 60 nM and 30 nM for HDAC2 and HDAC6, respectively. HDAC-IN-40 had antitumor effects
T6865 Quisinostat dihydrochloride Quisinostat 2HCl,Quisinostat (JNJ-26481585) 2HCl,JNJ26854165(Quisinostat) 2HCl,JNJ-26481585 2HCl Apoptosis , HDAC , Autophagy
Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; g...
T79541 HDAC-IN-61 HDAC
HDAC-IN-61 (compound 12k) is a potent, orally active inhibitor of histone deacetylase (HDAC) with anticancer activity, exhibiting an IC50 of 30 nM against Bel-7402 cells, and is utilized for cancer research [1].
T21329 Gemcitabine monophosphate disodium salt Gemcitabine monophosphate disodium salt monohydrate,Gemcitabine monophosphate disodium,GemMP
R306465 is a novel HDAC inhibitor with broad-spectrum antitumor activity against solid (IC50: 30 to 300 nM) and hematological malignancies. R306465 was found to be a potent inhibitor of HDAC1 and -8 (class I) in vitro.
T21898 MI-192
MI-192 is a selective HDAC2 and HDAC3 inhibitor with IC 50 s of 30 nM and 16 nM, respectively. MI-192 is more selective for HDAC2/3 than other HDAC isomers.MI-192 induces myeloid leukaemic cells apoptosis. MI-192 has pot...
T83946 CHDI 00484077
CHDI 00484077, a potent and selective class IIa histone deacetylase (HDAC) inhibitor, demonstrates significant efficacy with IC50 values ranging from 10-30 nM in vivo and specific activity at 0.01 nM and 0.04 nM in HEK29...
T83898 S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine SFN-Cys,D,L-Sulforaphane-L-cysteine
S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine (SFN-Cys) is an isothiocyanate derivative, functioning as an active metabolite of sulforaphane, a class I and II histone deacetylase (HDAC) inhibitor, and anticancer agen...
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