hbsag — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN1482	Chamaechromone		P450 , HBV
	Chamaechromone is a natural product isolated from the roots of Stellera chamaejasme L.. Chamaechromone has anti-HBV and insecticidal activity.		P450 , HBV
T27527	HBF-0259	HBF 0259	Antiviral
	HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells. HBF-0259 had a EC50 of approximately 1.5 microM in a secondary, HBV...		Antiviral
T12719	RG7834	RO 7020322	HBV
	RG7834 (RO 7020322) is a highly selective and orally bioavailable inhibitor of HBV(HBsAg and HBeAg and HBV DNA with IC50s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells).		HBV
T73440	Ccc_R08		HBV
	ccc_R08 is an orally available HBV cccDNA inhibitor that reduces extracellular levels of HBV DNA, HBsAg, and HBeAg in a dose-dependent manner. ccc_R08 is investigational for use in the treatment of HBV infections. ccc_R0...		HBV
T3794	Pentagalloylglucose	Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose	Influenza Virus
	1, 2, 3, 4, 6-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities. 2. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose (PGG) possesses poten...		Influenza Virus
T33679	Nirtetralin	(+-)-Nirtetralin
	Nirtetralin suppresses HBsAg and HBeAg expression.
TN6420	Sikokianin A
	Sikokianin A shows in vitro antiviral activity against HBsAg secretion.
T79469	HBV-IN-34		HBV
	HBV-IN-34 (compound 17i) is a potent inhibitor of HBsAg production, demonstrating remarkable in vitro anti-HBV efficacy with EC50 values of 0.018 μM for HBV DNA and 0.044 μM for HBsAg [1].		HBV
TN2220	Sophoranol	(+)-Sophoranol	HBV
	(+)-Sophoranol exhibits antiviral activity against the Coxsackie virus B3. It also shows potent anti-HBV activity with an inhibitory potency against HBsAg secretion and against HBeAg secretion.		HBV
TN4750	Periglaucine A		HBV
	Periglaucine A inhibits hepatitis B virus (HBV) surface antigen (HBsAg) secretion in Hep G2.2.15 cells.		HBV
TN4751	Periglaucine B		HBV
	Periglaucine B can inhibit hepatitis B virus (HBV) surface antigen (HBsAg) secretion in Hep G2.2.15 cells.		HBV
T62256	HBV-IN-11
	HBV-IN-11 is a potent inhibitor of HBsAg secretion (EC50: 0.46 μM).
T62144	HBV-IN-13
	HBV-IN-12 is a potent inhibitor of hepatitis B surface antigen (HBsAg).
T76969	Tuvirumab
	Tuvirumab (OST 577; SDZ-OST 577), a human IgG1 subclass monoclonal antibody, targets HBV surface antigen (HBsAg) by binding to it with high specificity and affinity (K=3.6 nM). This compound holds promise for research in...
T77063	Libivirumab
	Libivirumab (17.1.41), a humanized monoclonal antibody targeting hepatitis B virus (HBV), demonstrates neutralizing activity with half maximal inhibitory concentrations (IC50) of 35 ng/mL for HBsAg and 130 ng/mL for HBeA...
T79976	Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside		HBV
	Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside serves as an anti-hepatitis B virus (anti-HBV) agent, effectively inhibiting the secretion of HBV surface antigen (HBsAg) and HBV e antigen (HBeAg) in the Hep G2.2...		HBV
T23407	Surface antigen (208-215) [Hepatitis B Virus]		Others
	The nucleocapsid of the hepatitis B virus is covered by an envelope of HBV surface antigen (HBsAg), which has the common, group-specific determinant a. The four major subtypes of HBsAg, adw, adr, ayw and ayr, are generat...		Others
T76530	HBV Seq2 aa:208-216
	HBV Seq2 aa:208-216, a CD8 epitope peptide derived from HBsAg, is investigated within the context of the Large envelope protein from the Hepatitis B virus [1].
T62579	HBV-IN-19
	HBV-IN19 has inhibitory effects on hepatitis B virus (HBV) infection. HBV-IN19 inhibits HBsAg secretion and/or production and can be used in the study of HBV infection (e.g. chronic HBV infection).
T76528	Hepatitis b virus pre-s region (120-145)
	Hepatitis B Virus Pre-S Region (120-145) is a preS2 peptide that effectively blocks the attachment of single-chain Fv fragment (scFv) or IgG to recombinant Hepatitis B surface antigen (r-HBsAg) [1].