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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5097 | Ezatiostat | TER199(free base),TLK199 | Apoptosis , Glutathione Peroxidase , GST |
Ezatiostat (TER199(free base)) is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity. | |||
T22776 | Ezatiostat hydrochloride | TLK199 HCl,TER199 | Glutathione Peroxidase |
Ezatiostat hydrochloride (TLK199 HCl) is an effective inhibitor of glutathione S-transferase. Ezatiostat hydrochloride is a novel glutathione analog and the potential treatment of cytopenias. In addition, Ezatiostat hydr... | |||
T12189 | NBDHEX | Apoptosis , Glutathione Peroxidase , Autophagy | |
NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1) . | |||
T11504 | GSTO-IN-2 | Others | |
GSTO-IN-2 is a glutathione S-transferase inhibitor (IC50s: 1.4, 16.3, and 3.6 μM for GSTP1-1, GSTM1, and GSTA2). | |||
T39906 | LAS17 | LAS17 | |
LAS17, a potent and selective irreversible inhibitor targeting tyrosine in glutathione S-Transferase Pi (GSTP1), effectively inhibits GSTP1 activity, demonstrated by an IC50 value of 0.5 μM. | |||
T8424 | TLK117 | TER117 | Others |
TLK117 selective inhibits Glutathione S-transferase P1–1 (GSTP1-1)(Ki of 0.4 μM for GSTP). | |||
T74406 | BRD2889 | ||
BRD2889, an analog of the alkaloid piperlongumine, serves as a potent modulator of the GSTP1-ISCU axis in pulmonary hypertension (PH) [1]. | |||
T72328 | Cyclopropenone probe 1 | ||
Cyclopropenone probe 1 can specifically and efficiently modify a triple-negative breast cancer driver, glutathione S-transferase pi-1 (GSTP1) , by covalently binding at the catalytic active site. |