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Search Results for " gal1 "

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Targets

Neuropeptide Y Receptor

Compounds

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T8456	GALNON		Neuropeptide Y Receptor
	Galnon is a galanin receptor agonist, improves intrinsic cortical bone tissue properties		Neuropeptide Y Receptor
TP1993L	M617 acetate		Neuropeptide Y Receptor
	M617 acetate is a selective agonist of galanin receptor 1 (GAL1). M617 acetate acts through central GAL1, promotes GLUT4 expression, and enhances GLUT4 content in the cardiac muscle of type 2 diabetic rats. The Ki values...		Neuropeptide Y Receptor
T8559	Galnon TFA(475115-35-6(free base))		Neuropeptide Y Receptor
	Galnon is a novel non-peptide galanin receptor agonist (GAL1 and GAL2 with Ki of 11.7 and 34.1 μM respectively).		Neuropeptide Y Receptor
TP1994L	M871 acetate		Neuropeptide Y Receptor
	M871 acetate is a selective galanin GAL2 receptor antagonist (Ki values are 13.1 and 420 nM at GAL2 and GAL1 receptors, respectively).It blocks pronociceptive effects of GAL2 agonists including AR-M1896.		Neuropeptide Y Receptor
T38074	Thiodigalactoside		Galectin
	Thiodigalactoside (TDG), a non-metabolizable disaccharide, serves as an orally active, potent galectin (GAL) inhibitor, exhibiting Kd values of 24 μM and 49 μM for GAL1 and GAL3, respectively. Demonstrating anti-inflamma...		Galectin
TP1991L	M 1145 acetate		Neuropeptide Y Receptor
	M1145 acetate, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a Ki of 6.55 nM. M1145 acetate shows more than 90-fold higher affinity for GAL2 over GAL1 (Ki=587 nM) and a 76-fold higher af...		Neuropeptide Y Receptor
TP1992L	M40 acetate(143896-17-7 free base)		Neuropeptide Y Receptor
	M40 acetate is a potent, non-selective galanin receptor antagonist (Ki values are 1.82 and 5.1 nM at GAL1 and GAL2 respectively) that inhibits galanin (1-29) binding in rat brain in vitro (IC50 = 3 - 15 nM). Attenuates ...		Neuropeptide Y Receptor
T75817	M617 TFA
	M617 TFA, a selective galanin receptor 1 (GAL1) agonist, exhibits dissociation constants (Kis) of 0.23 nM for GAL1 and 5.71 nM for GAL2. Through activation of GAL1, M617 TFA enhances GLUT4 expression and content in the c...
TP1993	M617
	Selective galanin GAL1 receptor agonist (Ki values are 0.23 and 5.71 nM for GAL1 and GAL2 receptors respectively). Enhances food consumption in rats following i.c.v. administration and reduces CAP-induced inflammatory pa...
T37718	Galanin (rat, mouse) (trifluoroacetate salt)	GAL (rat, mouse),Galanin (rat, mouse) (trifluoroacetate salt)
	Galanin is a neuropeptide with diverse biological activities. [1][2][3][4][5] It binds to rat galanin (GAL) receptor subtypes GAL1-3 (IC50s = 0.339, 1.35, and 3.31 nM, respectively) and human GAL1-3 (IC50s = 0.288, 1.62,...
TP1994	M871
	Selective galanin GAL2 receptor antagonist (Ki values are 13.1 and 420 nM for GAL2 and GAL1 receptors respectively). Blocks the pro-nociceptive effect of GAL2 receptor agonists.
T73648	Galnon TFA
	Galnon TFA is a selective, non-peptide agonist specifically targeting the galanin receptors GAL1 and GAL2, demonstrating binding affinities (Kis) of 11.7 and 34.1 μM, respectively. This compound exhibits both anticonvuls...
TP1991	M1145	M 1145
	Potent and selective galanin receptor 2 (GAL2) agonist (EC50 = 38 nM, Ki values are 6.55, 497 and 587 nM at GAL2, GAL3 and GAL1 respectively). Has an additive effect on the signal transduction of galanin.
TP2028	Galanin (1-29)(rat, mouse)	Galanin (1-29) (rat, mouse)
	Non-selective galanin receptor agonist (Ki values are 0.98, 1.48 and 1.47 nM for GAL1, GAL2 and GAL3 respectively). Anticonvulsant; prevents the occurrence of full kindled seizures in rats.
T75818	Galanin (1-29)(rat, mouse) TFA
	Galanin (1-29)(rat, mouse) TFA acts as a non-selective agonist for galanin receptors, exhibiting affinities (Kis) of 0.98 nM for GAL1, 1.48 nM for GAL2, and 1.47 nM for GAL3, respectively. It possesses an anticonvulsant ...
TP1992	M40
	Potent, non-selective galanin receptor antagonist (Ki values are 1.82 and 5.1 nM at GAL1 and GAL2 respectively) that inhibits galanin (1-29) binding in rat brain in vitro (IC50 = 3 - 15 nM). Attenuates the antidepressant...
T82605	DB21, Galectin-1 Antagonist		Galectin
	DB21, Galectin-1 Antagonist, is a peptidomimetic conjugated with dibenzofuran, serving as an allosteric inhibitor of galectin-1 (GAL1) interactions with glycans on cell surfaces. This compound enhances the inhibition of ...		Galectin
T75819	M1145 TFA
	M1145 TFA, a chimeric peptide, acts as a selective agonist for the galanin receptor type 2 (GAL2), demonstrating a binding affinity (K i ) of 6.55 nM. It exhibits significantly greater selectivity for GAL2, with over 90-...
T38110	Galanin (Human) (Acetate)
	Galanin (Human) (Acetate) is a 30-amino acid neuropeptide and galanin (GAL) receptor agonist.It inhibits forskolin-induced cAMP production in HEK293E cells expressing recombinant human GAL1 receptors (EC50= 0.031 nM) and...

Cat No.	Product Name	Species	Expression System
TMPY-06685	Galectin-1 Protein, Human, Recombinant (His)	Human	E. coli
	Galectin-1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 16.07 kDa and the accession number is NP_002296.1.
TMPY-00976	Galectin-1 Protein, Human, Recombinant	Human	E. coli
	Galectin-1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 kDa and the accession number is A0A384MR27.
TMPK-00022	Galectin-1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Galectin 1 (Gal-1), a β-galactoside binding mammalian lectin of 14KDa, is implicated in many signalling pathways, immune responses associated with cancer progression and immune disorders. Inhibition of human Gal-1 has be...
TMPK-00829	Galectin-1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Galectin 1(Gal-1), a β-galactoside binding mammalian lectin of 14KDa, is implicated in many signalling pathways, immune responses associated with cancer progression and immune disorders. Inhibition of human Gal-1 has bee...
TMPY-02371	ST6GAL1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	ST6GAL1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.9 kDa and the accession number is Q64685.
TMPY-02093	ST6GAL1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ST6GAL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P15907.
TMPY-05265	ST6GAL1 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	ST6GAL1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P13721-1.