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15

Compounds

Cat No. Product Name Synonyms Targets
T7389 G15 Estrogen Receptor/ERR
G15 is a cell-permeable non-steroidal antagonist of GPER (Ki = 20 nM)
T11344 G150 DNA , cGAS
G150 inhibited interferon expression triggered by DSDNA with IC50 of 10.2 nM.G150 is an effective and highly selective inhibitor of human cyclic GMP-AMP synthase (H-CGAS).
T2034 AG1557 AG-1557,AG 1557 EGFR , HER
AG1557 (AG-1557) is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).
T17488 Azido-PEG15-t-butyl ester Others
Azido-PEG15-t-butyl ester is a polyethylene glycol (PEG) derived linker, specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
T17670 Boc-NH-PEG15-azide Others
Boc-NH-PEG15-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syste...
T18149 M-PEG15-alcohol Others
m-PEG15-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system w...
T15490 HO-PEG15-OH Others
HO-PEG15-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system withi...
T17414 Amino-PEG15-amine H2N-PEG15-CH2CH2NH2 Others
Amino-PEG15-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system...
T70391 AMG151 HCl
ARRY-403, also known as AMG-151, is an orally available allosteric glucokinase (GK) activator developed for the treatment of type 2 diabetes mellitus (T2DM). ARRY-403 has many favorable physicochemical characteristics an...
T17715 Cbz-N-PEG15-amine Others
Cbz-N-PEG15-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system...
T18150 M-PEG15-NHS ester Others
m-PEG15-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system...
T17968 Fmoc-NH-PEG15-CH2CH2COOH Others
Fmoc-NH-PEG15-CH2CH2COOH is a PEG-based PROTAC linker utilized for PROTAC synthesis[1].
T17487 Azido-PEG15-azide Others
Azido-PEG15-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system...
T17620 Bis-PEG15-acid Others
Bis-PEG15-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wi...
T17671 Boc-NH-PEG15-NH2 Others
Boc-NH-PEG15-NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system ...
TargetMol