15
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7389 | G15 | Estrogen Receptor/ERR | |
G15 is a cell-permeable non-steroidal antagonist of GPER (Ki = 20 nM) | |||
T11344 | G150 | DNA , cGAS | |
G150 inhibited interferon expression triggered by DSDNA with IC50 of 10.2 nM.G150 is an effective and highly selective inhibitor of human cyclic GMP-AMP synthase (H-CGAS). | |||
T2034 | AG1557 | AG-1557,AG 1557 | EGFR , HER |
AG1557 (AG-1557) is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194). | |||
T17488 | Azido-PEG15-t-butyl ester | Others | |
Azido-PEG15-t-butyl ester is a polyethylene glycol (PEG) derived linker, specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1]. | |||
T17670 | Boc-NH-PEG15-azide | Others | |
Boc-NH-PEG15-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syste... | |||
T18149 | M-PEG15-alcohol | Others | |
m-PEG15-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system w... | |||
T15490 | HO-PEG15-OH | Others | |
HO-PEG15-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system withi... | |||
T17414 | Amino-PEG15-amine | H2N-PEG15-CH2CH2NH2 | Others |
Amino-PEG15-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system... | |||
T70391 | AMG151 HCl | ||
ARRY-403, also known as AMG-151, is an orally available allosteric glucokinase (GK) activator developed for the treatment of type 2 diabetes mellitus (T2DM). ARRY-403 has many favorable physicochemical characteristics an... | |||
T17715 | Cbz-N-PEG15-amine | Others | |
Cbz-N-PEG15-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system... | |||
T18150 | M-PEG15-NHS ester | Others | |
m-PEG15-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system... | |||
T17968 | Fmoc-NH-PEG15-CH2CH2COOH | Others | |
Fmoc-NH-PEG15-CH2CH2COOH is a PEG-based PROTAC linker utilized for PROTAC synthesis[1]. | |||
T17487 | Azido-PEG15-azide | Others | |
Azido-PEG15-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system... | |||
T17620 | Bis-PEG15-acid | Others | |
Bis-PEG15-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wi... | |||
T17671 | Boc-NH-PEG15-NH2 | Others | |
Boc-NH-PEG15-NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system ... |