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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1776 | Plerixafor | JM3100,AMD 3100,AMD-3329 | Virus Protease , HIV Protease , CXCR |
Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4. | |||
T81135 | Sodium caseinates | ||
Sodium caseinate, the predominant milk protein salt of casein, promotes the proliferation and activation of granulocytes and elevates serum concentrations of cytokines GM-CSF and G-CSF, thereby inducing murine granulopoi... | |||
T4042 | Talabostat mesylate | Val-boroPro,PT100 | Proteasome , DPP-4 |
Talabostat mesylate (PT100) is an orally active, selective inhibitor of dipeptidyl peptidases IV (DPP4, IC50: 0.18 nM), including tumor-associated fibroblast activation protein. This agent may also stimulate the producti... | |||
T4650 | C188-9 | TTI-101 | Apoptosis , STAT |
C188-9 (TTI-101) is a Stat3 inhibitor with an IC50 of 4-7 μM. | |||
T82924 | Balugrastim | CG 10639 | |
Balugrastim (CG 10639), a novel long-acting recombinant granulocyte colony-stimulating factor (G-CSF), results from the genetic fusion of recombinant human serum albumin and G-CSF. It has applications in breast cancer re... | |||
T78328 | Efbemalenograstim alfa | F 627,Bineuta,Benegrastim | |
Efbemalenograstim alfa (F 627) is a recombinant fusion protein comprising a long-acting dimeric granulocyte colony-stimulating factor (G-CSF) with two human G-CSF molecules connected via a peptide linker to a human immun... | |||
T77172 | Eflapegrastim | ||
Eflapegrastim, a humanized IgG4 monoclonal antibody and granulocyte colony-stimulating factor (G-CSF), targets the G-CSF receptor (c-Fms). It promotes the proliferation and differentiation of neutrophil progenitor cells,... | |||
T33267 | Me6TREN 4HCl | Me6TREN Tetrahydrochloride,Me6-TREN Tetrahydrochloride,Me6 4HCl,Me 6 4HCl,Me-6 4HCl | |
Me6TREN 4HCl is a potent and efficacious mobilizing agent of hematopoietic stem and progenitor cells (HSPCs) that can act by activating MMP-9 expression and disrupting the SDF-1α/CXCR4 axis, exhibiting more significant m... | |||
T76908 | Anumigilimab | ||
Anumigilimab (CSL-324) is a humanized IgG2a monoclonal antibody (mAb) targeting the human granulocyte colony-stimulating factor (G-CSF) receptor, utilized to elevate neutrophil counts at inflammation sites [1] [2]. |