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Search Results for " fgf2 "

Targets

11

Compounds

10

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T73133 FGF22-IN-1 Others
FGF22-IN-1 is a potential CD4 N-terminal immunoglobulin variable region-like domain (CD4 D1) inhibitor.FGF22-IN-1 inhibits the interaction between CD4 and major histocompatibility complex (MHC) class II proteins and supp...
T5122 Alofanib RPT835 Apoptosis , FGFR
Alofanib (RPT835) is a selective allosteric inhibitor of FGFR2 and has a dramatic inhibitory effect on FGF2-induced phosphorylation of FRS2a in KATO III cells (IC50 <10 nM). It has no direct effect on FGF2-dependent FGFR...
T24804 SM27 SM-27,NSC-37204,SM 27,NSC37204 FGFR
SM27 is a fibroblast growth factor 2 (FGF2) inhibitor with anti-angiogenic activity and can be used to study tumours.
T26240 Surfen dihydrochloride Aminokinuride dihydrochloride,Aminoquinuride dihydrochloride,NSC-12155,Aminokinuride 2HCl,Aminoquinuride 2HCl FGFR , Antiviral , Antibiotic
Surfen dihydrochloride (Aminoquinuride dihydrochloride) is a potent small molecule antagonist of heparin sulfate with antibacterial and antiviral activity, and inhibits anthrax lethal factor, coagulation factor X, and le...
T28939 Tec-IN-21 TecIN21,Tec IN 21,Tec Inhibitor-21
Tec-IN-21 is an inhibitor of Tec kinase, it also blocks unconventional secretion of fibroblast growth factor 2 (FGF2).
T28938 Tec-IN-14 TecIN14
Tec-IN-14 is a Tec kinase inhibitor. Tec-IN-14 blocks unconventional secretion of fibroblast growth factor 2 (FGF2).
T36292 NSC 12
NSC 12 is an extracellular trap for fibroblast growth factor 2 (FGF2) that binds FGF2 (Kd = 51 μM) and interferes with its interaction with FGFR1, without affecting the ability of FGF2 to bind heparin or heparin sulfate ...
T23686 AHR-activator-1023 Branching Morphogenesis Modulator 1023,Cpd 1023,Compound 1023,BMM 1023
AHR-activator-1023 is the aryl hydrocarbon receptor activator. It is also a specific FGF2-induced branching morphogenesis modulator.
T28940 Tec-IN-6 Tec Inhibitor-6
Tec-IN-6 is an inhibitor of Tec kinase, it also blocks unconventional secretion of fibroblast growth factor 2 (FGF2).
TP1974 Obtustatin
Highly potent integrin α1β1 inhibitor (IC50 = 0.8 nM for α1β1 binding to type IV collagen). Selective for α1β1 over α2β1, αIIbβ3, αvβ3, α4β1, α5β6, α9β1 and α4β7. Inhibits FGF2-stimulated angiogenesis in the chicken chor...
T35807 C18 dihydro Ceramide (d18:0/18:0) C18 dihydro Ceramide (d18:0/18:0),Cer(d18:0/18:0)
C18 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C18 ceramide that lacks the 4,5-trans double bond. [1] Increased C18 dihydroceramide lipid levels lead to increased triacylglycer...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00037 FGF-2 Protein, Mouse, Recombinant Mouse E. coli
FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. The 17 kDa mo...
TMPJ-00842 FGF-2 Protein, Rat, Recombinant Rat E. coli
FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. ...
TMPJ-00039 FGF-2 Protein, Human, Recombinant (K128N) Human E. coli
Fibroblast growth factors (FGF) are a family of heparin-binding secreted proteins that stimulate cell proliferation and differentiation in a wide variety of tissues. FGFs play important roles in diverse biological functi...
TMPJ-00040 FGF-2 Protein, Human,Recombinant (Q65I, C96S, N111G) Human E. coli
Fibroblast growth factors (FGF) are a family of heparin-binding secreted proteins that stimulate cell proliferation and differentiation in a wide variety of tissues. FGFs play important roles in diverse biological functi...
TMPY-00749 FGF-2 Protein, Human, Recombinant Human E. coli
FGF-2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16.5 kDa and the accession number is P09038-4.
TMPH-00369 FGF-2 Protein, Chicken, Recombinant (His & Myc) Chicken E. coli
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Plays an important role in the regulation of cell survival, cell division, cell differentiation an...
TMPH-00368 FGF-2 Protein, Chicken, Recombinant (His) Chicken Yeast
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Plays an important role in the regulation of cell survival, cell division, cell differentiation an...
TMPY-01412 Glypican 5 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Glypican-5 (GPC5), is a cell membrane protein that belongs to the glypican family. The glypicans compose a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans that may play a role in the control...
TMPH-03203 FGFb Protein, Rabbit, Recombinant (His & SUMO) Rabbit E. coli
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell di...
TMPJ-01368 GPC1 Protein, Mouse, Recombinant (His) Mouse Human Cells
Glypican-1 is a cell membrane protein and belongs to the glypican family. The protein may act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfa...
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