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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP1263 | Fz7-21 | (Ac)-LPSDDLEFWCHVMY-NH2 | Wnt/beta-catenin |
Fz7-21 ((Ac)-LPSDDLEFWCHVMY-NH2) is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with e... | |||
T77692 | F7H | Wnt/beta-catenin , Antibacterial | |
F7H is a potent Frizzled receptor FZD7 antagonist with an IC50 value of 1.25 μM.F7H is a potent ligand for the transmembrane structural domain (TMD) of FZD7, with potential antitumor and bacteriostatic activity. | |||
T9662 | SRI 37892 | Wnt/beta-catenin | |
SRI 37892 is a Fzd7 inhibitor with potent activities against Wnt/β-catenin signaling and cancer cell viability. | |||
T75956 | Fz7-21 TFA | ||
Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) TFA, a potent peptide antagonist, selectively targets and binds to the FZD7 CRD subclass, significantly altering its CRD conformation and the structure of its lipid-binding groove. This com... | |||
T68468 | FJ9 | ||
FJ9 is a FZD7 inhibitor which disrupts protein-protein interaction between Frz7 and the PDZ domain of DVL, and induces apoptosis in melanoma cell line and non-small cell lung cancer cell line. | |||
TP1262 | Fz7-21 TFA (2247635-23-8 free base) | Fz7-21 TFA,(Ac)-LPSDDLEFWCHVMY-NH2 TFA | |
Fz7-21 TFA ((Ac)-LPSDDLEFWCHVMY-NH2 TFA), a peptide antagonist of Frizzled 7 (FZD 7) receptors, selectively binds to FZD7 CRD subclass. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively. |