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Cat No. | Product Name | Synonyms | Targets |
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T73133 | FGF22-IN-1 | Others | |
FGF22-IN-1 is a potential CD4 N-terminal immunoglobulin variable region-like domain (CD4 D1) inhibitor.FGF22-IN-1 inhibits the interaction between CD4 and major histocompatibility complex (MHC) class II proteins and supp... | |||
T5122 | Alofanib | RPT835 | Apoptosis , FGFR |
Alofanib (RPT835) is a selective allosteric inhibitor of FGFR2 and has a dramatic inhibitory effect on FGF2-induced phosphorylation of FRS2a in KATO III cells (IC50 <10 nM). It has no direct effect on FGF2-dependent FGFR... | |||
T24804 | SM27 | SM-27,NSC-37204,SM 27,NSC37204 | FGFR |
SM27 is a fibroblast growth factor 2 (FGF2) inhibitor with anti-angiogenic activity and can be used to study tumours. | |||
T26240 | Surfen dihydrochloride | Aminokinuride dihydrochloride,Aminoquinuride dihydrochloride,NSC-12155,Aminokinuride 2HCl,Aminoquinuride 2HCl | FGFR , Antiviral , Antibiotic |
Surfen dihydrochloride (Aminoquinuride dihydrochloride) is a potent small molecule antagonist of heparin sulfate with antibacterial and antiviral activity, and inhibits anthrax lethal factor, coagulation factor X, and le... | |||
T28939 | Tec-IN-21 | TecIN21,Tec IN 21,Tec Inhibitor-21 | |
Tec-IN-21 is an inhibitor of Tec kinase, it also blocks unconventional secretion of fibroblast growth factor 2 (FGF2). | |||
T28938 | Tec-IN-14 | TecIN14 | |
Tec-IN-14 is a Tec kinase inhibitor. Tec-IN-14 blocks unconventional secretion of fibroblast growth factor 2 (FGF2). | |||
T36292 | NSC 12 | ||
NSC 12 is an extracellular trap for fibroblast growth factor 2 (FGF2) that binds FGF2 (Kd = 51 μM) and interferes with its interaction with FGFR1, without affecting the ability of FGF2 to bind heparin or heparin sulfate ... | |||
T23686 | AHR-activator-1023 | Branching Morphogenesis Modulator 1023,Cpd 1023,Compound 1023,BMM 1023 | |
AHR-activator-1023 is the aryl hydrocarbon receptor activator. It is also a specific FGF2-induced branching morphogenesis modulator. | |||
T28940 | Tec-IN-6 | Tec Inhibitor-6 | |
Tec-IN-6 is an inhibitor of Tec kinase, it also blocks unconventional secretion of fibroblast growth factor 2 (FGF2). | |||
TP1974 | Obtustatin | ||
Highly potent integrin α1β1 inhibitor (IC50 = 0.8 nM for α1β1 binding to type IV collagen). Selective for α1β1 over α2β1, αIIbβ3, αvβ3, α4β1, α5β6, α9β1 and α4β7. Inhibits FGF2-stimulated angiogenesis in the chicken chor... | |||
T35807 | C18 dihydro Ceramide (d18:0/18:0) | C18 dihydro Ceramide (d18:0/18:0),Cer(d18:0/18:0) | |
C18 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C18 ceramide that lacks the 4,5-trans double bond. [1] Increased C18 dihydroceramide lipid levels lead to increased triacylglycer... |
Cat No. | Product Name | Species | Expression System |
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TMPJ-00842 | FGF-2 Protein, Rat, Recombinant | Rat | E. coli |
FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. ... | |||
TMPJ-00037 | FGF-2 Protein, Mouse, Recombinant | Mouse | E. coli |
FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. The 17 kDa mo... | |||
TMPJ-00039 | FGF-2 Protein, Human, Recombinant (K128N) | Human | E. coli |
Fibroblast growth factors (FGF) are a family of heparin-binding secreted proteins that stimulate cell proliferation and differentiation in a wide variety of tissues. FGFs play important roles in diverse biological functi... | |||
TMPJ-00040 | FGF-2 Protein, Human,Recombinant (Q65I, C96S, N111G) | Human | E. coli |
Fibroblast growth factors (FGF) are a family of heparin-binding secreted proteins that stimulate cell proliferation and differentiation in a wide variety of tissues. FGFs play important roles in diverse biological functi... | |||
TMPY-00749 | FGF-2 Protein, Human, Recombinant | Human | E. coli |
FGF-2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16.5 kDa and the accession number is P09038-4. | |||
TMPH-00369 | FGF-2 Protein, Chicken, Recombinant (His & Myc) | Chicken | E. coli |
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Plays an important role in the regulation of cell survival, cell division, cell differentiation an... | |||
TMPH-00368 | FGF-2 Protein, Chicken, Recombinant (His) | Chicken | Yeast |
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Plays an important role in the regulation of cell survival, cell division, cell differentiation an... | |||
TMPY-01412 | Glypican 5 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Glypican-5 (GPC5), is a cell membrane protein that belongs to the glypican family. The glypicans compose a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans that may play a role in the control... | |||
TMPH-03203 | FGFb Protein, Rabbit, Recombinant (His & SUMO) | Rabbit | E. coli |
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell di... | |||
TMPJ-01368 | GPC1 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Glypican-1 is a cell membrane protein and belongs to the glypican family. The protein may act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfa... |