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Search Results for " f2α "

20

Compounds

Cat No. Product Name Synonyms Targets
T35992 Ent-Prostaglandin F2α ent-Prostaglandin F2α
ent-Prostaglandin F2α is the enantiomer of PGF2α and is found in urine.
T36455 11β-Prostaglandin F2α 11β-Prostaglandin F2α
11β-Prostaglandin F2α is a bioactive metabolite catalyzed by AKR1C3 that stimulates prostaglandin F receptors and induces slug expression in breast cancer. 11β-Prostaglandin F2α is also an endogenous metabolite present i...
T38195 Prostaglandin F2α Ethanolamide Prostaglandin F2α Ethanolamide
Prostaglandin F2α ethanolamide (PGF2α-EA) is produced by COX-2 metabolism of the endogenous cannabinoid, arachidonoyl ethanolamide (AEA), found in brain, liver, and other mammalian tissues. AEA can be metabolized directl...
T37164 8-Isoprostaglandin F2α 8-iso Prostaglandin F2α
8-Isoprostaglandin F2α is a natural product for research related to life sciences. The catalog number is T37164 and the CAS number is 27415-26-5.
T37840 20-hydroxy Prostaglandin F2α 20-hydroxy Prostaglandin F2α
20-hydroxy Prostaglandin F2α (20-hydroxy PGF2α) is the ω-oxidation product of PGF2α. Cultured type II alveolar cells from pregnant rabbits metabolize exogenous PGF2α via microsomal cytochrome P450 ω-oxidation, producing ...
T37993 16,16-dimethyl Prostaglandin F2α 16,16-dimethyl Prostaglandin F2α
16,16-dimethyl Prostaglandin F2α can be used in related research in the field of life sciences. Its product number is T37993 and CAS number is 39746-23-1.
T37327 Prostaglandin F2α 1,15-lactone Prostaglandin F2α 1,15-lactone
PGF2α 1,15-lactone is a lipid-soluble internal ester of PGF2α. Hydrolysis of the lactone readily produces free PGF2α in plasma. In rhesus monkeys, a total dose of 15 mg of PGF2α 1,15-lactone terminates early pregnancy, w...
T38196 Prostaglandin F2α isopropyl ester Prostaglandin F2α isopropyl ester
PGF2α isopropyl ester is an ester prodrug of PGF2α with enhanced lipid solubility. Due to better membrane penetration, PGF2α isopropyl ester is more suitable than PGF2α or PGF2α tromethamine salt for topical application ...
T37946 17-trifluoromethylphenyl trinor Prostaglandin F2α 17-trifluoromethylphenyl trinor Prostaglandin F2α
A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma. Of these, the unsubstituted or meta-substituted aromatic derivatives are the most pote...
T37275 2,3-dinor-11β-Prostaglandin F2α 2,3-dinor-11β-Prostaglandin F2α
2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where it represented approximately 1% and 4% of the infused radiol...
T36146 13,14-dihydro Prostaglandin F2α 13,14-dihydro Prostaglandin F2α,13,14-dihydro PGF2α
13,14-dihydro Prostaglandin F2α (13,14-dihydro PGF2α) is the analog of PGF2α which has no unsaturation in the lower side chain. It causes luteolysis in hamsters with a potency five times higher than PGF2α. The ED50 value...
T36617 Ent-8-iso Prostaglandin F2α ent-8-iso Prostaglandin F2α
ent-8-iso Prostaglandin F2α is a potent vasoconstrictor of porcine retinal and cerebral microvessels with EC50 values of 30.6 and 53.5 nM, respectively.
T37995 16-phenoxy tetranor Prostaglandin F2α 16-phenoxy tetranor Prostaglandin F2α
16-phenoxy PGF2α is a metabolically stable analog of PGF2α. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α.
T37991 15-keto Prostaglandin F2α 15-keto Prostaglandin F2α,15-keto PGF2α Endogenous Metabolite , Prostaglandin Receptor
15-keto Prostaglandin F2α is a metabolite of Prostaglandin F2α that lowers intraocular pressure in rabbits.
T36166 8-iso-15-keto Prostaglandin F2α 8-iso-15-keto Prostaglandin F2α
8-iso-15-keto Prostaglandin F2α (8-iso-15-keto PGF2α) is a metabolite of the isoprostane 8-iso PGF2α in rabbits, monkeys, and humans. 8-isoprostane (8-iso PGF2α) is a prostaglandin-like product of non-specific lipid pero...
T37326 Prostaglandin F2α 1,11-lactone Prostaglandin F2α 1,11-lactone,PGF2α 1,11-lactone Prostaglandin Receptor
Prostaglandin F2α 1,11-lactone (PGF2α 1,11-lactone) is a lipid-soluble prodrug of Prostaglandin F2α and can be used in studies about treating glaucoma. Prostaglandin F2α 1,11-lactone is active as an antifertility agent w...
T37948 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α
A number of 17-phenyl trinor prostaglandin F2α(17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma.1,2,3Of these, the ones wherein the 13,14-double bond has been hydrogenated retain relat...
T37937 16-phenoxy tetranor Prostaglandin F2α methyl ester 16-phenoxy tetranor Prostaglandin F2α methyl ester
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostag...
T37947 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester
Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 17-trifluoromethylphenyl trinor PGF2α is an analog of PGF2α that shares the meta-triflu...
T37943 17-phenyl trinor Prostaglandin F2α isopropyl ester 17-phenyl trinor Prostaglandin F2α isopropyl ester
17-phenyl trinor PGF2α N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost. The N-ethyl amide prostaglandin prod...

Compounds

ent-Prostaglandin F2α
T35992
Synonym: ent-Prostaglandin F2α
Target:
11β-Prostaglandin F2α
T36455
Synonym: 11β-Prostaglandin F2α
Target:
Prostaglandin F2α Ethanolamide
T38195
Synonym: Prostaglandin F2α Ethanolamide
Target:
8-Isoprostaglandin F2α
T37164
Synonym: 8-iso Prostaglandin F2α
Target:
20-hydroxy Prostaglandin F2α
T37840
Synonym: 20-hydroxy Prostaglandin F2α
Target:
16,16-dimethyl Prostaglandin F2α
T37993
Synonym: 16,16-dimethyl Prostaglandin F2α
Target:
Prostaglandin F2α 1,15-lactone
T37327
Synonym: Prostaglandin F2α 1,15-lactone
Target:
Prostaglandin F2α isopropyl ester
T38196
Synonym: Prostaglandin F2α isopropyl ester
Target:
17-trifluoromethylphenyl trinor Prostaglandin F2α
T37946
Synonym: 17-trifluoromethylphenyl trinor Prostaglandin F2α
Target:
2,3-dinor-11β-Prostaglandin F2α
T37275
Synonym: 2,3-dinor-11β-Prostaglandin F2α
Target:
13,14-dihydro Prostaglandin F2α
T36146
Synonym: 13,14-dihydro Prostaglandin F2α,13,14-dihydro PGF2α
Target:
ent-8-iso Prostaglandin F2α
T36617
Synonym: ent-8-iso Prostaglandin F2α
Target:
16-phenoxy tetranor Prostaglandin F2α
T37995
Synonym: 16-phenoxy tetranor Prostaglandin F2α
Target:
15-keto Prostaglandin F2α
T37991
Synonym: 15-keto Prostaglandin F2α,15-keto PGF2α
Target: Endogenous Metabolite, Prostaglandin Receptor
8-iso-15-keto Prostaglandin F2α
T36166
Synonym: 8-iso-15-keto Prostaglandin F2α
Target:
Prostaglandin F2α 1,11-lactone
T37326
Synonym: Prostaglandin F2α 1,11-lactone,PGF2α 1,11-lactone
Target: Prostaglandin Receptor
17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α
T37948
Synonym: 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α
Target:
16-phenoxy tetranor Prostaglandin F2α methyl ester
T37937
Synonym: 16-phenoxy tetranor Prostaglandin F2α methyl ester
Target:
17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester
T37947
Synonym: 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester
Target:
17-phenyl trinor Prostaglandin F2α isopropyl ester
T37943
Synonym: 17-phenyl trinor Prostaglandin F2α isopropyl ester
Target:
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TargetMol