20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T35992 | Ent-Prostaglandin F2α | ent-Prostaglandin F2α | |
ent-Prostaglandin F2α is the enantiomer of PGF2α and is found in urine. | |||
T36455 | 11β-Prostaglandin F2α | 11β-Prostaglandin F2α | |
11β-Prostaglandin F2α is a bioactive metabolite catalyzed by AKR1C3 that stimulates prostaglandin F receptors and induces slug expression in breast cancer. 11β-Prostaglandin F2α is also an endogenous metabolite present i... | |||
T38195 | Prostaglandin F2α Ethanolamide | Prostaglandin F2α Ethanolamide | |
Prostaglandin F2α ethanolamide (PGF2α-EA) is produced by COX-2 metabolism of the endogenous cannabinoid, arachidonoyl ethanolamide (AEA), found in brain, liver, and other mammalian tissues. AEA can be metabolized directl... | |||
T37164 | 8-Isoprostaglandin F2α | 8-iso Prostaglandin F2α | |
8-Isoprostaglandin F2α is a natural product for research related to life sciences. The catalog number is T37164 and the CAS number is 27415-26-5. | |||
T37840 | 20-hydroxy Prostaglandin F2α | 20-hydroxy Prostaglandin F2α | |
20-hydroxy Prostaglandin F2α (20-hydroxy PGF2α) is the ω-oxidation product of PGF2α. Cultured type II alveolar cells from pregnant rabbits metabolize exogenous PGF2α via microsomal cytochrome P450 ω-oxidation, producing ... | |||
T37993 | 16,16-dimethyl Prostaglandin F2α | 16,16-dimethyl Prostaglandin F2α | |
16,16-dimethyl Prostaglandin F2α can be used in related research in the field of life sciences. Its product number is T37993 and CAS number is 39746-23-1. | |||
T37327 | Prostaglandin F2α 1,15-lactone | Prostaglandin F2α 1,15-lactone | |
PGF2α 1,15-lactone is a lipid-soluble internal ester of PGF2α. Hydrolysis of the lactone readily produces free PGF2α in plasma. In rhesus monkeys, a total dose of 15 mg of PGF2α 1,15-lactone terminates early pregnancy, w... | |||
T38196 | Prostaglandin F2α isopropyl ester | Prostaglandin F2α isopropyl ester | |
PGF2α isopropyl ester is an ester prodrug of PGF2α with enhanced lipid solubility. Due to better membrane penetration, PGF2α isopropyl ester is more suitable than PGF2α or PGF2α tromethamine salt for topical application ... | |||
T37946 | 17-trifluoromethylphenyl trinor Prostaglandin F2α | 17-trifluoromethylphenyl trinor Prostaglandin F2α | |
A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma. Of these, the unsubstituted or meta-substituted aromatic derivatives are the most pote... | |||
T37275 | 2,3-dinor-11β-Prostaglandin F2α | 2,3-dinor-11β-Prostaglandin F2α | |
2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where it represented approximately 1% and 4% of the infused radiol... | |||
T36146 | 13,14-dihydro Prostaglandin F2α | 13,14-dihydro Prostaglandin F2α,13,14-dihydro PGF2α | |
13,14-dihydro Prostaglandin F2α (13,14-dihydro PGF2α) is the analog of PGF2α which has no unsaturation in the lower side chain. It causes luteolysis in hamsters with a potency five times higher than PGF2α. The ED50 value... | |||
T36617 | Ent-8-iso Prostaglandin F2α | ent-8-iso Prostaglandin F2α | |
ent-8-iso Prostaglandin F2α is a potent vasoconstrictor of porcine retinal and cerebral microvessels with EC50 values of 30.6 and 53.5 nM, respectively. | |||
T37995 | 16-phenoxy tetranor Prostaglandin F2α | 16-phenoxy tetranor Prostaglandin F2α | |
16-phenoxy PGF2α is a metabolically stable analog of PGF2α. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α. | |||
T37991 | 15-keto Prostaglandin F2α | 15-keto Prostaglandin F2α,15-keto PGF2α | Endogenous Metabolite , Prostaglandin Receptor |
15-keto Prostaglandin F2α is a metabolite of Prostaglandin F2α that lowers intraocular pressure in rabbits. | |||
T36166 | 8-iso-15-keto Prostaglandin F2α | 8-iso-15-keto Prostaglandin F2α | |
8-iso-15-keto Prostaglandin F2α (8-iso-15-keto PGF2α) is a metabolite of the isoprostane 8-iso PGF2α in rabbits, monkeys, and humans. 8-isoprostane (8-iso PGF2α) is a prostaglandin-like product of non-specific lipid pero... | |||
T37326 | Prostaglandin F2α 1,11-lactone | Prostaglandin F2α 1,11-lactone,PGF2α 1,11-lactone | Prostaglandin Receptor |
Prostaglandin F2α 1,11-lactone (PGF2α 1,11-lactone) is a lipid-soluble prodrug of Prostaglandin F2α and can be used in studies about treating glaucoma. Prostaglandin F2α 1,11-lactone is active as an antifertility agent w... | |||
T37948 | 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α | 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α | |
A number of 17-phenyl trinor prostaglandin F2α(17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma.1,2,3Of these, the ones wherein the 13,14-double bond has been hydrogenated retain relat... | |||
T37937 | 16-phenoxy tetranor Prostaglandin F2α methyl ester | 16-phenoxy tetranor Prostaglandin F2α methyl ester | |
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostag... | |||
T37947 | 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester | 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester | |
Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 17-trifluoromethylphenyl trinor PGF2α is an analog of PGF2α that shares the meta-triflu... | |||
T37943 | 17-phenyl trinor Prostaglandin F2α isopropyl ester | 17-phenyl trinor Prostaglandin F2α isopropyl ester | |
17-phenyl trinor PGF2α N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost. The N-ethyl amide prostaglandin prod... |