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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15249 | Estrogen receptor modulator 1 | Estrogen Receptor/ERR | |
Estrogen receptor modulator 1 causes regression of Tamoxifen-resistant, hormone-independent xenograft tumors. Estrogen receptor modulator 1 is an orally active and selective estrogen receptor modulator (SERM) (pIC50: 0.4... | |||
T78646 | Estrogen receptor antagonist 8 | Estrogen Receptor/ERR | |
Estrogen Receptor Antagonist 8 exhibits potent antagonistic activity against the estrogen receptor (ER), demonstrating effective anti-uterotrophic potential in vivo, with an EC50 value of 4.160 μM. | |||
T11236 | Giredestrant tartrate | Estrogen receptor antagonist 1 | Estrogen Receptor/ERR , Others |
Giredestrant tartrate (Estrogen receptor antagonist 1) is a novel, orally active, selective and effective non-steroidal estrogen receptor antagonist. Giredestrant tartrate strongly binds to ER, resulting in the failure o... | |||
T11237 | Camizestrant | Estrogen receptor antagonist 2 | Estrogen Receptor/ERR |
Camizestrant (Estrogen receptor antagonist 2) is an antagonist of the estrogen receptor and can be used in studies about ER+ HER2-advanced breast cancer[1]. | |||
T40893 | Estrogen receptor modulator 6 | ||
Estrogen receptor modulator 6 (compound 3a) is a highly specific and potent agonist of the estrogen receptor (ER) β with a remarkable affinity (K i = 0.44 nM). This compound exhibits an impressive 19-fold selectivity for... | |||
T19988 | Conjugated Estrogen sodium | Conjugated estrogens,Conest,HSDB 3076,Kestrin,Estrogens, conjugated,TAG-39 | |
Conjugated estrogens are medicine that contains a mixture of estrogen hormones. It is used to treat moderate to severe hot flashes, changes in and around the vagina, and other symptoms of menopause or low amounts of estr... | |||
T63277 | Estrogen receptor antagonist 2 | ||
Estrogen receptor antagonist 2 is a selective down-regulator of estrogen receptor. Estrogen (E2) and estrogen alpha receptor (ERα) are important drivers of breast cancer development. estrogen receptor antagonist 2 has re... | |||
T63914 | Estrogen receptor antagonist 3 | ||
Estrogen receptor antagonist 3 is a potent degradation agent of the estrogen receptor (ER). Estrogen signalling systems play an important role in the regulation of cell growth, differentiation and apoptosis, and Estrogen... | |||
T63106 | Estrogen receptor antagonist 4 | ||
Estrogen Receptor Antagonist 4 is a potent inhibitor of the estrogen receptor (ER), crucial for regulating cell growth, differentiation, and apoptosis. This compound holds promise for cancer research[1]. | |||
T79109 | Estrogen receptor modulator 8 | Estrogen Receptor/ERR | |
Estrogen Receptor Modulator 8 (compound 4) is an orally active inhibitor targeting Estrogen Receptor/ERR α with potent efficacy (IC50 = 0.437 nM in MCF-7 cells) and effectively hampers MCF-7 cell proliferation (IC50 = 0.... | |||
T62952 | Estrogen receptor antagonist 5 | ||
Estrogen receptor antagonist 5 is a potent antagonist of the Estrogen receptor. Estrogen receptor (Estrogen receptor) is a ligand-activated transcriptional regulatory protein that interacts with endogenous estrogens and ... | |||
T63582 | Estrogen receptor antagonist 1 | ||
Estrogen receptor antagonist 1 is a potent antagonist of the estrogen receptor. Estrogen receptor antagonist 1 has shown research potential in breast cancer disease. | |||
T79064 | Estrogen receptor modulator 7 | Estrogen Receptor/ERR | |
Estrogen Receptor Modulator 7 is a potent modulator of estrogen receptors, utilized in cancer research [1]. | |||
T60293 | Estrogen receptor-IN-1 | ||
Estrogen receptor-IN-1 (compound 16) is an effective estrogen receptor (ER) inhibitor with IC 50 s of 13, 5μM for ERα and Erβ, respectively [1]. | |||
T62953 | Estrogen receptor antagonist 6 | ||
Estrogen receptor antagonist 6 is a potent antagonist of the Estrogen receptor. Estrogen receptor is a ligand-activated transcriptional regulatory protein that interacts with endogenous estrogens and mediates the inducti... | |||
T61909 | Estrogen receptor antagonist 7 | ||
Estrogen Receptor Antagonist 7 (Compound 13) is a potent antagonist of estrogen receptors (ER), demonstrating antiproliferative effects against breast and ovarian cancer cells, along with anticancer and anti-uterotrophic... | |||
T82439 | Estrogen receptor modulator 10 | Estrogen Receptor/ERR | |
Compound G-5b, an estrogen receptor modulator 10, functions as an estrogen receptor (ER) antagonist (IC50=6.7 nM) and degrader (DC50=0.4 nM). It has the capability to induce apoptosis and block cells at the G1/G0 phase, ... | |||
T62311 | Estrogen receptor β antagonist 2 | ||
Estrogen receptor β antagonist 2 is a selective, potent estrogen receptor β (ERβ) antagonist that acts on Erα (IC50: 109.10 μM) and Erβ (IC50: 0.63 μM). | |||
T62764 | Estrogen receptor α antagonist 1 | ||
Estrogen receptor α antagonist 1 (compound 35) is a highly selective estrogen receptor α antagonist that acts on estrogen receptor α (IC50: 0.02 μM), estrogen receptor β (IC50. Estrogen receptor α antagonist 1 (compound ... | |||
T4388 | PHTPP | Estrogen Receptor/ERR , Estrogen/progestogen Receptor | |
PHTPP is a selective ERβ antagonist. |