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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1166 | Ellipticine | NSC 71795,Elliptisine | Topoisomerase |
Ellipticine (Elliptisine) is a potent antineoplastic agent exhibiting multiple mechanisms of action, IC50 of 0.67±0.06, 1.25±0.13, 1.25±0.13, 0.67±0.06, 0.27±0.02, 0.49±0.04, 0.44±0.03, and 1.48±0.62 μM for Leukemia HL-6... | |||
T4614 | Ellipticine hydrochloride | Ellipticine HCl,NSC 71795 (hydrochloride) | Topoisomerase |
Ellipticine hydrochloride (NSC-71795 (hydrochloride)) is a potent antineoplastic agent; inhibits DNA topoisomerase II activities. | |||
T69109 | Ellipticine tartrate | ||
Ellipticine tartrate is a DNA intercalating agent and a DNA topoisomerase II inhibitor. | |||
T68788 | Ellipticine quinone | ||
Ellipticine quinone, also known as NSC-383230, is a Drp1 inhibitor. rpitor1 and Drpitor1a inhibited the GTPase activity of Drp1 without inhibiting the GTPase of dynamin 1. Ellipticine quinone showed greater potency tha... | |||
T82560 | Di-Ellipticine-RIBOTAC | PROTACs | |
Di-Ellipticine-RIBOTAC is a bifunctional small molecule that effectively diminishes the r(G4C2) repeat expansion associated with c9ALS/FTD both in vitro and in vivo, showcasing therapeutic potential in amyotrophic latera... | |||
T7747 | Datelliptium chloride hydrochloride | DNA/RNA Synthesis | |
Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities. | |||
T36699 | 9-Methoxyellipticine | ||
9-Methoxyellipticine is an alkaloid and a derivative of the DNA intercalating agent ellipticine that has been found in O. maculataand has anticancer activity.It intercalates into DNA and is an inhibitor of wild-type c-Ki... | |||
T27562 | Hydroxyellipticine-1a | ||
Hydroxyellipticine-1a, a selective r(CGG)exp probe, improves pre-mRNA splicing defects, inhibits formation of nuclear inclusions and RANT in a FXTAS cellular mode.l | |||
T10200 | 9-Hydroxyellipticine hydrochloride | Others | |
9-Hydroxyellipticine hydrochloride is a inhibitor of Topo II and RyR. It exhibits antitumor, antioxidant and catecholamine-releasing activities. 9-Hydroxyellipticine hydrochloride inihibits Hela S-3 and 293T cells (IC50s... | |||
T26401 | 9-Hydroxyellipticin free base | IGIG929,NSC 210717,9-hydroxyellipticine,IGIG 929,9-Hydroxyellipticin,Hydroxyellipticine | |
9-hydroxyellipticine is a potent cytotoxic and antitumor agent. 9-hydroxyellipticine is a 9-hydroxy derivative of ellipticine. | |||
T7429 | Datelliptium chloride | DNA/RNA Synthesis | |
Datelliptium chloride is a DNA-intercalating agent derived from ellipticine. Datelliptium chloride shows anti-tumor activities. | |||
T41151 | K34c | ||
K34c is a potent and selective α5β1 integrin inhibitor (IC50 = 3.1 nM). K34c inhibits cell survival and migration, inhibits p53-dependent senescence induced by Temozolomide or Ellipticine and promotes apoptosis in U87MG ... |