Home Tools
Log in
Cart

Search Result

Search Results for " erα "

20

Compounds

Cat No. Product Name Synonyms Targets
T39727 ERα degrader-2 ERK
ERα degrader-2 is a selective and potent estrogen receptor (SERD) degrader with anticancer activity, inhibits ERα, and has an EC50 value for estrogen receptor degradation of 0.3 nM.ERα degrader-2 can be used for the prev...
T18605 PROTAC ERα Degrader-2 Others
PROTAC ERα Degrader-2 is composed of a cIAP1 ligand binding group, a linker, and an estrogen receptor α (ERα) binding group, serving as an ERα degrader. It achieves maximal ERα degradation in human mammary tumor MCF7 cel...
T18636 PROTAC ERα Degrader-1 Others
PROTAC ERα Degrader-1 is a chemical compound. It consists of a ubiquitin E3 ligase binding group, a linker, and a protein binding group. This compound serves as a degrader of estrogen receptor-alpha (ERα).
T63922 ERα degrader 5
ERα degrader 5 is an orally active, selective estrogen receptor (ER) reducer that acts on ERα (EC50: 1.1 nM). ERα degrader 5 shows anti-tumour effects in vivo.
T64026 ERα antagonist 1
ERα antagonist 1 is a selective, potent, covalent estrogen receptor alpha (ERα) antagonist that blocks the cell cycle of MCF-7 cells in G0/G1 phase and induces apoptosis.
T78676 ERα degrader 6 Estrogen Receptor/ERR
ERα degrader 6 (Compound 31q) is an ERα degrader with a K I of 75 nM and also inhibits ARO with an IC50 value of 37.7 nM. It effectively inhibits tumor growth in the MCF-7 tumor xenograft model and has applications in br...
T17940 Estrone-N-O-C1-amido ERα ligand 1 Others
Estrone-N-O-C1-amido (ERα ligand 1) is an estrogen ligand derived from Estrone that specifically binds to estrogen receptor α (ERα). Through a linker, Estrone-N-O-C1-amido (ERα ligand 1) forms a complex with the cIAP1 li...
T74375 PROTAC ERα Y537S degrader-1
PROTAC ERα Y537S degrader-1 comprises a ubiquitin E3 ligase binding group, a linker and a protein binding group. PROTAC ERα Y537S degrader-1 is an estrogen receptor-alpha (ERα) Y537S degrader [1] .
T79736 14-3-3σ/ERα stabilizer-1 Estrogen Receptor/ERR
Compound 181, also known as 14-3-3σ/ERα Stabilizer-1, is a covalent stabilizer targeting the 14-3-3σ/ERα proteins. It is utilized in research as a molecular glue [1].
T2544 Bazedoxifene acetate WAY-TES 424,TSE 424,WAY-140424 Estrogen Receptor/ERR , Estrogen/progestogen Receptor
Bazedoxifene acetate (WAY-TES 424) is a novel selective estrogen receptor modulator (SERM).
T6404 Bazedoxifene hydrochloride Bazedoxifene HCl,TSE-424 Estrogen Receptor/ERR , Estrogen/progestogen Receptor
Bazedoxifene hydrochloride (TSE-424) is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of 23 nM and 89 nM, respectively.
T5633 H3B-5942 Estrogen Receptor/ERR , Estrogen/progestogen Receptor
H3B-5942 belongs to a class of ERα antagonists referred to as selective estrogen receptor covalent antagonists (SERCA).
T16566 Propyl pyrazole triol PPT Estrogen Receptor/ERR , Estrogen/progestogen Receptor
Propyl pyrazole triol (PPT) is a selective agonist of estrogen receptor alpha. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: ...
T3846 Bavachin Corylifolin Estrogen Receptor/ERR , Estrogen/progestogen Receptor
Bavachin (Corylifolin) is a phytoestrogen that activates the estrogen receptors ERα and ERβ.
T26537 AC-186 AC186,AC 186 Estrogen/progestogen Receptor
AC-186 is a nonsteroidal estrogen receptor β (ERβ) agonist with different affinities for ERβ and ERα, with an EC50 of 6 nM for ERβ and 5000 nM for ERα. AC-186 has neuroprotective activity and has been used in the study o...
T13674 Elacestrant RAD1901 Estrogen Receptor/ERR , Estrogen/progestogen Receptor
Elacestrant (RAD1901) with IC50s of 48 and 870 nM for ERα and ERβ, respectively.Elacestrant  is an orally available selective estrogen receptor degrader .
T6533 Hexestrol Bibenzyl,Hexanoestrol,meso-Hexestrol,Hexestrofen Estrogen Receptor/ERR , Estrogen/progestogen Receptor
Hexestrol (Hexanoestrol) binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively.
T3975 AZD9496 Estrogen Receptor/ERR , Estrogen/progestogen Receptor
AZD9496 is an orally available selective estrogen receptor(ERα) antagonist, with potential antineoplastic activity.
T13675 Elacestrant dihydrochloride RAD1901 dihydrochloride Estrogen/progestogen Receptor
Elacestrant dihydrochloride (DA-DKRAD1901 dihydrochloride) is an orally available selective estrogen receptor degrader with IC50s of 48 for ERα and 870 nM for ERβ, respectively.
T13443 (R)-Equol (+)-Equol Estrogen/progestogen Receptor
(R)-Equol ((+)-Equol) is an ERα and ERβ agonist with Kis of 27.4 and 15.4 nM, respectively.

Compounds

ERα degrader-2
T39727
Synonym:
Target: ERK
PROTAC ERα Degrader-2
T18605
Synonym:
Target: Others
PROTAC ERα Degrader-1
T18636
Synonym:
Target: Others
ERα degrader 5
T63922
Synonym:
Target:
ERα antagonist 1
T64026
Synonym:
Target:
ERα degrader 6
T78676
Synonym:
Target: Estrogen Receptor/ERR
Estrone-N-O-C1-amido
T17940
Synonym: ERα ligand 1
Target: Others
PROTAC ERα Y537S degrader-1
T74375
Synonym:
Target:
14-3-3σ/ERα stabilizer-1
T79736
Synonym:
Target: Estrogen Receptor/ERR
Bazedoxifene acetate
T2544
Synonym: WAY-TES 424,TSE 424,WAY-140424
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor
Bazedoxifene hydrochloride
T6404
Synonym: Bazedoxifene HCl,TSE-424
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor
H3B-5942
T5633
Synonym:
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor
Propyl pyrazole triol
T16566
Synonym: PPT
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor
Bavachin
T3846
Synonym: Corylifolin
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor
AC-186
T26537
Synonym: AC186,AC 186
Target: Estrogen/progestogen Receptor
Elacestrant
T13674
Synonym: RAD1901
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor
Hexestrol
T6533
Synonym: Bibenzyl,Hexanoestrol,meso-Hexestrol,Hexestrofen
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor
AZD9496
T3975
Synonym:
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor
Elacestrant dihydrochloride
T13675
Synonym: RAD1901 dihydrochloride
Target: Estrogen/progestogen Receptor
(R)-Equol
T13443
Synonym: (+)-Equol
Target: Estrogen/progestogen Receptor
1 2 3 4 5
TargetMol