eed — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T12553	PROTAC EED degrader-1		Others
	PROTAC EED degrader-1 is a PROTAC targeting EED (pKD = 9.02), is a inhibitor of polycomb repressive complex 2 (PRC2) with pIC50 of 8.17.		Others
T12554	PROTAC EED degrader-2		Others
	PROTAC EED degrader-2 is a PROTAC targeting EED (pKD of 9.27),is a inhibitor of polycomb repressive complex 2 (PRC2) with pIC50 of 8.11.		Others
T3458	EED226		Histone Methyltransferase
	EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.		Histone Methyltransferase
T61825	EED ligand 1
	EED ligand 1 is a highly versatile, potent, and effective inhibitor that specifically targets the EED subunit of the polycomb repressive complex 2 (PRC2) methyltransferase.
T17649	Boc-GABA-OH		Others , PROTAC Linker
	Boc-GABA-OH serves as a PROTAC linker essential for synthesizing UNC6852, an EED-targeted PROTAC[1].		Others , PROTAC Linker
T13954	UNC6852		Histone Methyltransferase , Ligands for Target Protein for PROTAC
	UNC6852 contains an EED ligand (IC50 = 247 nM) and a von Hippel-Lindau ligand and is a selective polycomb repressive complex 2 (PRC2) degrader based on PROTAC.
T9681	MAK-683 hydrochloride		Histone Methyltransferase
	MAK683 hydrochloride is an inhibitor of embryonic ectoderm development (EED). MAK683 exhibits IC50s of 59, 26, 89 nM in EED Alphascreen binding, ELISA and LC-MS assay.		Histone Methyltransferase
T17931	EED226-COOH		Others
	EED226-COOH, derived from EED226, serves as a ligand targeting the EED protein for PROTAC applications. It attaches to a VHL ligand through a linker, culminating in the formation of UNC6852, which specifically degrades P...		Others
T22322	EEDi-5285	UM-EEDi-5285,EEDI5285	Histone Methyltransferase
	EEDi-5285, an orally active and highly potent inhibitor targeting embryonic ectoderm development (EED) protein, exhibits anti-cancer activity. It demonstrates exceptional efficacy with an IC50 value of 0.2 nM, indicating...		Histone Methyltransferase
T6520	Grape Seed Extract	Grape Seed P.E.	Apoptosis , Others
	Grape Seed Extract (Grape Seed P.E.) is exudate from seeds of the grape plant Vitis vinifera, composed of oils and secondary plant metabolites (BIOFLAVONOIDS and polyphenols) credited with important medicinal properties.		Apoptosis , Others
T40223	EEDi-5273
	EEDi-5273 is a highly potent and orally efficacious inhibitor of EED, with an approximate IC50 value of 0.2 nM. This compound exhibits exceptional activity, capable of achieving complete and persistent regression of tumo...
T13626	Cottonseed oil		Others
	Cottonseed oil, a cooking oil extracted from the seeds of cotton plants, has been considered the most insecticidal of vegetable oils.		Others
T124238	Rheediaxanthone A
	Rheediaxanthone A is a useful organic compound for research related to life sciences and the catalog number is T124238.
T71923	EEDQ
	EEDQ is an irreversible dopamine-receptor antagonist.EEDQ is also a highly specific reagent for carboxyl groups. It enables the coupling of acylamino acids with amino acid esters in high yield and without racemization.
T76665	Z-LEED-FMK
	Z-LEED-FMK is a chemical compound that acts as an inhibitor for caspase-13 and caspase-4. Additionally, it impedes caspase-1 processing in S. typhimurium-infected macrophages [1] [2].
T15201	MAK683		Histone Methyltransferase
	MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay).		Histone Methyltransferase
T10205	A-395		Histone Methyltransferase
	A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions that potently inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12, IC50: 18 nM).		Histone Methyltransferase
T13765	MAK683-CH2CH2COOH		Others
	MAK683-CH2CH2COOH binds to EED (embryonic ectoderm development protein). MAK683-CH2CH2COOH and a VHL ligand for the E3 ubiquitin ligase have been used to design EED-Targeted PROTAC which are EED degrader-1 and PROTAC EED...		Others
T18673	(S,R,S)-AHPC-O-Ph-PEG1-NH2	VH032-O-Ph-PEG1-NH2	Others
	(S,R,S)-AHPC-O-Ph-PEG1-NH2 (VH032-O-Ph-PEG1-NH2) serves as an E3 ligase ligand-linker conjugate, integrating a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is utilized in PROTAC EED degrader-...		Others
T73945	MAK683-CH2CH2COOH hydrochloride
	MAK683-CH2CH2COOH, targeting embryonic ectoderm development protein (EED), alongside a VHL ligand for E3 ubiquitin ligase, contributes to the formulation of PROTAC EED degrader-1 and PROTAC EED degrader-2 [1].